Potency of Antimicrobial, Antioxidant and Cytotoxic Activities from Fractions Streptomyces MA02

Streptomyces sp. MA02 is potential to produce various biological activities. In previous research, its extract shows antimicrobial activities. In this study, extract prepared from Streptomyces sp. MA02 stored at -80 oC was re-evaluated the antimicrobial activity on various medium and incubation time...

Full description

Saved in:
Bibliographic Details
Published in:Journal of applied pharmaceutical science 2013-05, Vol.3 (4), p.S68-S70
Main Authors: Jayuska, Afghani, Ardiningsih, Puji, Mabella, Tika, Nofiani, Risa
Format: Article
Language:English
Subjects:
Streptomyces
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Streptomyces sp. MA02 is potential to produce various biological activities. In previous research, its extract shows antimicrobial activities. In this study, extract prepared from Streptomyces sp. MA02 stored at -80 oC was re-evaluated the antimicrobial activity on various medium and incubation time to find out storage effect toward the antimicrobial activity. We also evaluated n-hexane and ethyl acetic fractions toward the antimicrobial, antioxidant and toxicity activities. The extract Streptomyces sp. MA02 still inhibit tested microorganisms eventhough it decreases 50% than the extract prepared from Streptomyces sp. MA02 without -80 oC storage. Antimicrobial activity was only exhibited by the methanolic fraction Streptomyces sp. MA02. The methanolic and n-hexane fractions showed cytotoxic eventhough it was not for antioxidant activity in the linoleic acid system with ferrothiocyanate reagent (FTC).
ISSN:2231-3354
DOI:10.7324/JAPS.2013.34.S12