METABOLIC PARAMETERS CONCENTRATIONS IN BLOOD SERUM OF CZECH PIED BULLS DEPENDING ON SINGLE NUCLEOTIDE POLYMORPHISM OF LEPTIN GENE

The aim of present study was to test hypothesis, that the leptin gene single nucleotide polymorphism (C/T) giving missense mutation (Arg25Cys) has an effect on concentration of blood serum total cholesterol, beta-hydroxybutyrate and urea in cattle. The experiment were performed in 58 Czech Pied bull...

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Bibliographic Details
Published in:Journal of microbiology, biotechnology and food sciences biotechnology and food sciences, 2014-02, Vol.3 (Special Issue 2 (Biotechnology)), p.145-147
Main Authors: Pavlik, Ales, Slama, Petr, Havlicek, Zdenek, Filipcik, Radek
Format: Article
Language:English
Subjects:
Adipocytes
Body fat
Cattle
Cholesterol
Energy
Feeds
Hypotheses
Metabolism
Metabolites
Nutritional status
Polymorphism
Proteins
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Summary:The aim of present study was to test hypothesis, that the leptin gene single nucleotide polymorphism (C/T) giving missense mutation (Arg25Cys) has an effect on concentration of blood serum total cholesterol, beta-hydroxybutyrate and urea in cattle. The experiment were performed in 58 Czech Pied bulls at 240 ± 9 days of age, which were divided in three experimental groups depending on different leptin genotypes (CC, n=28; CT, n=21; TT, n=9). Resulting genotypes in the exon 2 were CC (48.3%), CT (36.2%), and TT (15.5%). There were no differences in serum total cholesterol, urea, beta-hydroxybutyrate concentrations among the genotypes. Based on our results we may assume that analysed SNP of leptin gene have no effect on nutritional status and energy balance in fattened cattle.
ISSN:1338-5178