Highly Efficient Antibacterial Surface Grafted with a Triclosan-Decorated Poly(N‑Hydroxyethylacrylamide) Brush

This work presented a highly efficient antibacterial Ti-surface which was grafted with poly­(N-hydroxyethylacrylamide) (PHEAA) brush and further decorated with triclosan (TCS). The modified surfaces were characterized using contact angle measurements, X-ray photoelectron spectroscopy, and attenuated...

Full description

Saved in:
Bibliographic Details
Published in:ACS applied materials & interfaces 2015-04, Vol.7 (12), p.7008-7015
Main Authors: Wu, Hai-Xia, Tan, Lei, Tang, Zhao-Wen, Yang, Mei-Yan, Xiao, Jian-Yun, Liu, Chuan-Jun, Zhuo, Ren-Xi
Format: Article
Language:English
Subjects:
Acrylic Resins - chemistry
Acrylic Resins - pharmacology
Actinomyces - drug effects
Actinomyces - physiology
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - pharmacology
Bacterial Adhesion - drug effects
Streptococcus mutans - drug effects
Streptococcus mutans - physiology
Surface Properties
Triclosan - chemistry
Triclosan - pharmacology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This work presented a highly efficient antibacterial Ti-surface which was grafted with poly­(N-hydroxyethylacrylamide) (PHEAA) brush and further decorated with triclosan (TCS). The modified surfaces were characterized using contact angle measurements, X-ray photoelectron spectroscopy, and attenuated total reflectance Fourier transform infrared. The antibacterial performance of the modified surfaces was evaluated using the Streptococcus mutans and Actinomyces naeslundii attachment test. The Ti surface with PHEAA brush (Ti-PHEAA) was able to resist the adhesion of the bacteria, while the TCS-decorated Ti surface (Ti-TCS) showed the capability of killing the bacteria adhered on the surface. As we coupled the TCS to the PHEAA brush, the surface showed highly efficient antibacterial performance due to the combination of the resistance to the bacteria adhesion and its activity of killing bacteria.
ISSN:1944-8244
1944-8252
DOI:10.1021/acsami.5b01210