Evaluation of cord blood ischemia modified albumin in normal pregnancies and pre-eclampsia

Objective: Pre-eclampsia is associated with ischemia and increased oxidative stress, which may lead to modification of plasma albumin to ischemia modified albumin (IMA). Methods: IMA levels were estimated in cord blood of 30 newborns born to pre-eclamptic mothers and compared with 30 normal newborns...

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Bibliographic Details
Published in:Hypertension in pregnancy 2015-05, Vol.34 (2), p.204-208
Main Authors: Dahiya, Kiran, Kulshrestha, Manish Raj, Bansal, Piyush, Ghalaut, Veena Singh, Kulshrestha, Rupita, Dahiya, Priya, Dhupper, Vasudha
Format: Article
Language:English
Subjects:
Adult
Biomarkers - blood
Case-Control Studies
Cord blood
Female
Fetal Blood - chemistry
Humans
Infant, Newborn
Ischemia
Ischemia modified albumin
Oxidative Stress
Pre-eclampsia
Pre-Eclampsia - blood
Pregnancy - blood
Serum Albumin
Serum Albumin, Human
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Summary:Objective: Pre-eclampsia is associated with ischemia and increased oxidative stress, which may lead to modification of plasma albumin to ischemia modified albumin (IMA). Methods: IMA levels were estimated in cord blood of 30 newborns born to pre-eclamptic mothers and compared with 30 normal newborns. IMA was estimated colorimetrically and the results were compared statistically. Results: The levels of IMA were found to be significantly higher (p 
ISSN:1064-1955
1525-6065
DOI:10.3109/10641955.2014.1001901