A Turn-On Fluorescent Probe for Detecting Nitric Oxide in Aqueous Media

Imaging of nitric oxide (NO) in living cells can provide new insights in understanding unsolved pathways in the cardiovascular and neurological dysfunction and many types of cancers. For the detection of NO under physiological conditions, we synthesized a turn-on fluorescent probe comprising CdSe/Zn...

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Bibliographic Details
Published in:Journal of nanomaterials 2014-01, Vol.2014 (2014), p.1-5
Main Authors: Koo, Eunhae, Lee, Jong-Chul
Format: Article
Language:English
Subjects:
Aqueous solutions
Cadmium selenides
Cancer
Displacement
Emission
Fluorescence
Free radicals
Intermetallics
Nanomaterials
Nitric oxide
Quantum dots
Quenching (cooling)
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Summary:Imaging of nitric oxide (NO) in living cells can provide new insights in understanding unsolved pathways in the cardiovascular and neurological dysfunction and many types of cancers. For the detection of NO under physiological conditions, we synthesized a turn-on fluorescent probe comprising CdSe/ZnS quantum dots (QDs) coordinated with dirhodium complex. Emission from CdSe/ZnS-QDs is quenched when coordinated with the dirhodium complex but can be restored upon the displacement by nitric oxide.
ISSN:1687-4110
1687-4129
DOI:10.1155/2014/276057