Outcomes and resource use of non-small cell lung cancer (NSCLC) patients treated with first-line platinum-based chemotherapy across Europe: FRAME prospective observational study

Highlights • FRAME was a prospective observational study conducted across 11 countries in Europe. • 1564 NSCLC patients initiating FLT between 2009 and 2011 were observed in FRAME. • Real-world treatment patterns, survival, and resource use from FRAME are reported. • FRAME provides insight into rout...

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Published in:Lung cancer (Amsterdam, Netherlands) Netherlands), 2015-05, Vol.88 (2), p.215-222
Main Authors: Moro-Sibilot, Denis, Smit, Egbert, de Castro Carpeño, Javier, Lesniewski-Kmak, Krzysztof, Aerts, Joachim, Villatoro, Rosa, Kraaij, Kees, Nacerddine, Karim, Dyachkova, Yulia, Smith, Karen T, Taipale, Kaisa, Girvan, Allicia C, Visseren-Grul, Carla, Schnabel, Philipp A
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Carcinoma, Non-Small-Cell Lung - drug therapy
Cisplatin - administration & dosage
Deoxycytidine - administration & dosage
Deoxycytidine - analogs & derivatives
Europe
Female
Health resources
Hematology, Oncology and Palliative Medicine
Humans
Lung Neoplasms - drug therapy
Male
Middle Aged
Non-small cell lung cancer (NSCLC)
Observational study
Organoplatinum Compounds - administration & dosage
Pemetrexed - administration & dosage
Prospective Studies
Pulmonary/Respiratory
Survival
Taxoids - administration & dosage
Vinblastine - administration & dosage
Vinblastine - analogs & derivatives
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Summary:Highlights • FRAME was a prospective observational study conducted across 11 countries in Europe. • 1564 NSCLC patients initiating FLT between 2009 and 2011 were observed in FRAME. • Real-world treatment patterns, survival, and resource use from FRAME are reported. • FRAME provides insight into routine clinical practice and real-world patient outcomes.
ISSN:0169-5002
1872-8332
DOI:10.1016/j.lungcan.2015.02.011