Epidermal nevi with aberrant epidermal structure in keratinocytes and melanocytes

Epidermal nevi are congenital cutaneous hamartomas caused by embryonic somatic mutations. Ultrastructural features of adult epidermal nevi have rarely been investigated. Herein, we report a case involving a Japanese adult who had epidermal nevi with right congenital blindness and a right accessory n...

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Published in:Journal of dermatology 2015-04, Vol.42 (4), p.408-410
Main Authors: Oiso, Naoki, Sugawara, Koji, Yonamine, Ayano, Tsuruta, Daisuke, Kawada, Akira
Format: Article
Language:English
Subjects:
Adult
cutaneous hamartoma
electron microscopy
epidermal nevus
Female
Hamartoma - pathology
Humans
keratinocytes
Keratinocytes - pathology
melanocytes
Melanocytes - pathology
Nevus - pathology
Skin Diseases - pathology
Skin Neoplasms - pathology
Studies
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cited_by cdi_FETCH-LOGICAL-c4337-3a1da877ed51d78c61b03400640f512664951100912e0ec892b0fd4e5eb02fee3
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container_end_page 410
container_issue 4
container_start_page 408
container_title Journal of dermatology
container_volume 42
creator Oiso, Naoki
Sugawara, Koji
Yonamine, Ayano
Tsuruta, Daisuke
Kawada, Akira
description Epidermal nevi are congenital cutaneous hamartomas caused by embryonic somatic mutations. Ultrastructural features of adult epidermal nevi have rarely been investigated. Herein, we report a case involving a Japanese adult who had epidermal nevi with right congenital blindness and a right accessory nipple. The histopathologic and ultrastructural studies showed divergent abnormal epidermal structures in both melanocytes and keratinocytes. Our case indicates the need to further investigate histopathologic, ultrastructural, and genetic associations in adult epidermal nevi.
doi_str_mv 10.1111/1346-8138.12787
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source Wiley-Blackwell Read & Publish Collection
subjects Adult
cutaneous hamartoma
electron microscopy
epidermal nevus
Female
Hamartoma - pathology
Humans
keratinocytes
Keratinocytes - pathology
melanocytes
Melanocytes - pathology
Nevus - pathology
Skin Diseases - pathology
Skin Neoplasms - pathology
Studies
title Epidermal nevi with aberrant epidermal structure in keratinocytes and melanocytes
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