Voice Quality in Laryngotracheal Stenosis: Impact of Dilation and Level of Stenosis

• Published in: Annals of otology, rhinology & laryngology rhinology & laryngology, 2015-05, Vol.124 (5), p.413-418
• Main Authors: Hillel, Alexander T., Karatayli-Ozgursoy, Selmin, Benke, James R., Best, Simon, Pacheco-Lopez, Paulette, Teets, Kristine, Starmer, Heather, Akst, Lee M.
• Format: Article
• Language: English
• Subjects: Adult; Dilatation - methods; Female; Follow-Up Studies; Humans; Laryngostenosis - diagnosis; Laryngostenosis - physiopathology; Laryngostenosis - therapy; Male; Middle Aged; Retrospective Studies; Severity of Illness Index; Tracheal Stenosis - diagnosis; Tracheal Stenosis - physiopathology; Tracheal Stenosis - therapy; Treatment Outcome; Voice Quality
• ISSN: 0003-4894; 1943-572X
• DOI: 10.1177/0003489414564249

Objective: To assess the impact of suspension microlaryngoscopy with balloon dilation on voice-related quality of life (V-RQOL) in laryngotracheal stenosis (LTS). Methods: Retrospective chart review of LTS patients dilated at a tertiary-care academic hospital from 2010 to 2013. Data were obtained and then analyzed. LTS was stratified by (1) subglottic or tracheal stenosis and (2) multilevel stenosis (MLS; glottic and subglottic/tracheal). Pre- and postoperative V-RQOL and grade, roughness, breathiness, asthenia, strain (GRBAS) scores were compared. The number and frequency of balloon dilation procedures over the lifetime were secondary outcome variables. Results: Thirty-eight patients were identified: 26 subglottic/tracheal and 12 multilevel. Of these, 71.4% required multiple dilations, with greatest dilations/patient for multilevel stenosis (4.8). V-RQOL improved in the 27 patients with completed pre- and postoperative scores from a mean of 70.4 to 80 (P = .025). Pre/postoperative V-RQOLs for tracheal/subglottic (mean, 82.8/93.8) were significantly higher (P = .0001/.0001) than multilevel stenosis (48/55.3). Voice quality-of-life improvement was significant for the subglottic/tracheal cohort (P = .036) but not for the MLS group. GRBAS was performed pre- and postoperatively in 10 patients with improvement in all domains except breathiness. Conclusion: Laryngotracheal stenosis is associated with dysphonia. Patients with glottic involvement have significantly worse voice quality of life than those with tracheal/subglottic stenosis. Endoscopic balloon dilation improves V-RQOL in patients with subglottic/tracheal stenosis.