Apatite formation abilities of various carrageenan gels in simulated body environment

Organic–inorganic hybrids with apatite-forming abilities in physiological environments offer possibilities for building flexible bone-bonding bioactive materials; several functional groups are known to induce apatite nucleation. Here, bioactive organic–inorganic hybrids from κ-carrageenan and λ-carr...

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Bibliographic Details
Published in:Journal of the Ceramic Society of Japan 2010/06/01, Vol.118(1378), pp.487-490
Main Authors: NAKATA, Ryo, MIYAZAKI, Toshiki, MORITA, Yumi, ISHIDA, Eiichi, IWATSUKI, Ryota, OHTSUKI, Chikara
Format: Article
Language:English
Subjects:
Apatite
Carrageenan
Ceramics
Crosslinking
Hydrogels
Nucleation
Organic–inorganic hybrid
Releasing
Simulated body fluid (SBF)
Simulation
Sulphonic groups
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Summary:Organic–inorganic hybrids with apatite-forming abilities in physiological environments offer possibilities for building flexible bone-bonding bioactive materials; several functional groups are known to induce apatite nucleation. Here, bioactive organic–inorganic hybrids from κ-carrageenan and λ-carrageenan containing sulfonic groups were prepared. Carrageenan hydrogels were made by cross-linking with CaCl2. The apatite-forming abilities of each kind of carrageenan hydrogel were examined using simulated body fluid (SBF); λ-carrageenan was found to be superior to κ-carrageenan for this purpose. The former swelled significantly in aqueous conditions, releasing a large amount of Ca2+ ions into the SBF, contributing to rapid apatite formation.
ISSN:1882-0743
1348-6535
DOI:10.2109/jcersj2.118.487