Sol–gel synthesis, microstructure and adsorption properties of hollow silica spheres

Spherical colloidal particles with a hollow interior and a mesoporous shell are particularly useful for drug delivery and release because such spheres combine the unique properties of hollow interior (for storing the drug) with mesoporous shell (for controlled release). Hollow silica spheres (HSS) w...

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Published in:Materials letters 2011-06, Vol.65 (12), p.1811-1814
Main Authors: Fan, Haitao, Lei, Zhibin, Pan, Jia Hong, Zhao, X.S.
Format: Article
Language:English
Subjects:
Adsorption
Controlled release
Drug delivery systems
drugs
High speed tool steels
Microstructure
Polystyrene resins
polystyrenes
Porous materials
Shells
silica
Silicon dioxide
Sol gel process
Sol–gel preparation
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description Spherical colloidal particles with a hollow interior and a mesoporous shell are particularly useful for drug delivery and release because such spheres combine the unique properties of hollow interior (for storing the drug) with mesoporous shell (for controlled release). Hollow silica spheres (HSS) with a mesoporous shell were prepared via a sol–gel process in the presence of dual templates polystyrene spheres and cetyltrimethylammonium bromide for creating the hollow core and mesopore shell. The effect of the ratio of silica precursor over polystyrene spheres on particle morphology and pore structure of the HSS was investigated. The adsorption kinetics of methyl blue on the HSS was evaluated and correlated with the mesoporous shell structure.
doi_str_mv 10.1016/j.matlet.2011.03.045
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subjects Adsorption
Controlled release
Drug delivery systems
drugs
High speed tool steels
Microstructure
Polystyrene resins
polystyrenes
Porous materials
Shells
silica
Silicon dioxide
Sol gel process
Sol–gel preparation
title Sol–gel synthesis, microstructure and adsorption properties of hollow silica spheres
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