Forensic applications of desorption electrospray ionisation mass spectrometry (DESI-MS)

Abstract Desorption electrospray ionisation mass spectrometry (DESI-MS) is an emerging analytical technique that enables in situ mass spectrometric analysis of specimens under ambient conditions. It has been successfully applied to a large range of forensically relevant materials. This review assess...

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Bibliographic Details
Published in:Forensic science international 2013-03, Vol.226 (1), p.10-21
Main Authors: Morelato, Marie, Beavis, Alison, Kirkbride, Paul, Roux, Claude
Format: Article
Language:English
Subjects:
Analytical chemistry
Atmospheric pressure
Chemical warfare agents (CWAs)
Chemical Warfare Agents - chemistry
Chromatography
Coloring Agents - chemistry
Dermatoglyphics
Desorption
Desorption electrospray ionisation mass spectrometry (DESI-MS)
Drugs
Explosive Agents - chemistry
Explosives
Firearms
Forensic engineering
Forensic science
Forensic Sciences
Gunshot residues (GSR)
Humans
Illicit drugs
Ink
Mass spectrometry
Mathematical analysis
Pathology
Pharmaceutical Preparations - chemistry
Residues
Skin - chemistry
Spectrometry, Mass, Electrospray Ionization
Street Drugs - chemistry
Toxicology
Urine
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Summary:Abstract Desorption electrospray ionisation mass spectrometry (DESI-MS) is an emerging analytical technique that enables in situ mass spectrometric analysis of specimens under ambient conditions. It has been successfully applied to a large range of forensically relevant materials. This review assesses and highlights forensic applications of DESI-MS including the analysis and detection of illicit drugs, explosives, chemical warfare agents, inks and documents, fingermarks, gunshot residues and drugs of abuse in urine and plasma specimens. The minimal specimen preparation required for analysis and the sensitivity of detection achieved offer great advantages, especially in the field of forensic science.
ISSN:0379-0738
1872-6283
DOI:10.1016/j.forsciint.2013.01.011