New interpretation of heat effects in polymorphic transitions

Overlapping endothermic and exothermic effects in DSC measurements of polymorphic transitions is often detected in molecular crystals and drugs. It is explained by the sequence of melting and crystallization. In this paper, we argue that this explanation is incorrect. In revealing the kinetic nature...

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Bibliographic Details
Published in:Journal of thermal analysis and calorimetry 2013-07, Vol.113 (1), p.419-424
Main Authors: Drebushchak, V. A., Drebushchak, Tatiana N., Boldyreva, Elena V.
Format: Article
Language:English
Subjects:
Analytical Chemistry
Calorimetry
Chemistry
Chemistry and Materials Science
Crystallization
Crystals
Differential scanning calorimetry
Endothermic reactions
Inorganic Chemistry
Measurement Science and Instrumentation
Melting
Nucleation
Physical Chemistry
Polymer Sciences
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Summary:Overlapping endothermic and exothermic effects in DSC measurements of polymorphic transitions is often detected in molecular crystals and drugs. It is explained by the sequence of melting and crystallization. In this paper, we argue that this explanation is incorrect. In revealing the kinetic nature of the endo/exo thermal effect, we suggest another explanation, based on the nucleation. New interpretation does allow us to measure the energetic barrier in the nucleation of bulk sample, thus providing a tool for testing the nucleation models.
ISSN:1388-6150
1588-2926
1572-8943
DOI:10.1007/s10973-013-3120-5