Purple discoloration of the colon found during autopsy: Identification of betanin, its aglycone and metabolites by liquid chromatography–high-resolution mass spectrometry

Highlights • Autopsy finding of purple discoloration of the colon. • Identification of betanin/betanidin by high resolution MS as cause of discoloration. • Betanidin glucuronide and sulfate identified as phase II metabolites in urine.

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Bibliographic Details
Published in:Forensic science international 2014-07, Vol.240, p.e1-e6
Main Authors: Roemmelt, Andreas T, Franckenberg, Sabine, Steuer, Andrea E, Kraemer, Thomas
Format: Article
Language:English
Subjects:
Adult
Autopsies
Beta vulgaris
Betacyanins - isolation & purification
Betacyanins - urine
Betanidine
Betanin
Chromatography
Chromatography, Liquid
Colon
Colon - chemistry
Colon - pathology
Coloring Agents - isolation & purification
Discoloration
Forensic Pathology
Forensic sciences
Humans
Intestinal Mucosa - chemistry
LC–HRMS
Liquids
Male
Mass Spectrometry
Membranes
Metabolites
Pathology
Purple colon
Sulfates
Urine
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Description
Summary:Highlights • Autopsy finding of purple discoloration of the colon. • Identification of betanin/betanidin by high resolution MS as cause of discoloration. • Betanidin glucuronide and sulfate identified as phase II metabolites in urine.
ISSN:0379-0738
1872-6283
DOI:10.1016/j.forsciint.2014.03.016