Myocardial toxoplasmosis complicating cardiac transplant

The increase in numbers of immunocompromised patients has been reflected by an increasing frequency of opportunistic infections. Of these, Toxoplasma gondii has been reported as a significant human pathogen following cardiac transplantation. In this setting, quiescent toxoplasma myocardial cysts may...

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Bibliographic Details
Published in:Cardiovascular pathology 1996-03, Vol.5 (2), p.101-104
Main Authors: Dressler, Frederick A., Javier, Julian J., Salinas-Madrigal, Luis, Milligan, Thomas W., McBride, Lawrence R., Labovitz, Arthur J., Miller, Leslie W.
Format: Article
Language:English
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Summary:The increase in numbers of immunocompromised patients has been reflected by an increasing frequency of opportunistic infections. Of these, Toxoplasma gondii has been reported as a significant human pathogen following cardiac transplantation. In this setting, quiescent toxoplasma myocardial cysts may become active after implantation into a therapeutically immunosuppressed host. The consequences of infection are significant and carry a high morbidity and mortality. We present the clinical and pathologic characteristics of a patient with toxoplasma infection complicating cardiac transplant and review previously reported cases of this entity.
ISSN:1054-8807
1879-1336
DOI:10.1016/1054-8807(95)00068-2