Decolonization of Children After Incision and Drainage for MRSA Abscess: A Retrospective Cohort Study

Background/Purpose. Whether decolonization following incision and drainage (I&D) for methicillin-resistant Staphylococcus aureus (MRSA) abscess decreases repeat I&D and MRSA-positive cultures in children is unknown. Materials/Methods. Referral to the Pediatric Infectious Disease Service (PID...

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Bibliographic Details
Published in:Clinical pediatrics 2015-05, Vol.54 (5), p.445-450
Main Authors: Finnell, S. Maria E., Rosenman, Marc B., Christenson, John C., Downs, Stephen M.
Format: Article
Language:English
Subjects:
Abscess - surgery
Administration, Intranasal
Anti-Bacterial Agents - administration & dosage
Baths - methods
Child
Child, Preschool
Children & youth
Cohort Studies
Disinfectants - administration & dosage
Drainage
Female
Humans
Longitudinal Studies
Male
Methicillin-Resistant Staphylococcus aureus - drug effects
Mupirocin - administration & dosage
Patients
Pediatrics
Regression analysis
Retrospective Studies
Risk Factors
Sodium Hypochlorite - administration & dosage
Staphylococcal Infections - therapy
Staphylococcus infections
Treatment Outcome
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Summary:Background/Purpose. Whether decolonization following incision and drainage (I&D) for methicillin-resistant Staphylococcus aureus (MRSA) abscess decreases repeat I&D and MRSA-positive cultures in children is unknown. Materials/Methods. Referral to the Pediatric Infectious Disease Service (PIDS) for decolonization was determined for eligible children (2003-2010), with outcomes studied over 12 months. Results. We identified 653 children; 54 had been seen by PIDS. In the PIDS group, no patients (0/54, 0%) had a repeat I&D. In the no PIDS group 36/599 (6%) had a repeat I&D, P = .06. Logistic regression modeling for repeat I&D showed no significant effect, odds ratio = 0.29; 95% confidence interval = 0.04-2.15; P = .23. In the PIDS group, 3 patients (3/54, 5.6%) had a repeat MRSA-positive culture. In the no PIDS group, 58/599 (9.7%) had a positive repeat culture, P = .46. Logistic regression modeling for positive culture showed no significant effect (odds ratio = 0.55; 95% confidence interval = 0.17-1.81; P = .32). Conclusions. We detected no statistically significant association between decolonization and repeat I&D or MRSA-positive culture.
ISSN:0009-9228
1938-2707
DOI:10.1177/0009922814556059