What We Know and What We Do Not Know About Factors Associated with and Interventions to Promote Antiretroviral Adherence

Antiretroviral therapy (ART) adherence remains critical for achieving successful outcomes. Factors affecting ART adherence can occur at the individual level or be related to the treatment regimen, daily schedule, and/or interpersonal relationships. While treatment-related barriers have diminished wi...

Full description

Saved in:
Bibliographic Details
Published in:Current infectious disease reports 2015-04, Vol.17 (4), p.466-466, Article 13
Main Authors: Mannheimer, Sharon, Hirsch-Moverman, Yael
Format: Article
Language:English
Subjects:
Antiretroviral agents
Antiretroviral drugs
Compliance
HIV
HIV/AIDS (R MacArthur
Human immunodeficiency virus
Infectious Diseases
Intervention
Medicine
Medicine & Public Health
Section Editor
Topical Collection on HIV/AIDS
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Antiretroviral therapy (ART) adherence remains critical for achieving successful outcomes. Factors affecting ART adherence can occur at the individual level or be related to the treatment regimen, daily schedule, and/or interpersonal relationships. While treatment-related barriers have diminished with recent simplified ART regimens, guidelines still recommend considering regimen simplicity. ART readiness should be assessed prior to starting ART, with follow-up adherence assessments once ART is initiated, and at all subsequent clinical visits. Adherence interventions work best when multifaceted, targeted for at-risk and nonadherent participants, and tailored to individuals’ needs. Successful interventions have included education and counseling, provision of social support, directly observed therapy, and financial incentives. Pillboxes and two-way short-text messaging service (SMS) reminders have been shown to be effective and are widely recommended tools for promoting ART adherence. Further research is needed to determine the optimal combination of adherence interventions, as well as generalizability, implementation, and cost-effectiveness.
ISSN:1523-3847
1534-3146
DOI:10.1007/s11908-015-0466-9