c-Fos induction in mesotelencephalic dopamine pathway projection targets and dorsal striatum following oral intake of sugars and fats in rats

• Published in: Brain research bulletin 2015-02, Vol.111, p.9-19
• Main Authors: Dela Cruz, J.A.D, Coke, T, Karagiorgis, T, Sampson, C, Icaza-Cukali, D, Kest, K, Ranaldi, R, Bodnar, R.J
• Format: Article
• Language: English
• Subjects: Amygdala - metabolism; Animals; Basolateral amygdala; Brain - metabolism; Central-cortico-medial amygdala; Corn Oil - administration & dosage; Dopaminergic Neurons - metabolism; Dorsal striatum; Eating; Fructose - administration & dosage; Glucose - administration & dosage; Infralimbic medial prefrontal cortex; Male; Neostriatum - metabolism; Neurology; Neurons - metabolism; Nucleus Accumbens - metabolism; Nucleus accumbens core; Nucleus accumbens shell; Polysaccharides, Bacterial - administration & dosage; Prefrontal Cortex - metabolism; Prelimbic medial prefrontal cortex; Proto-Oncogene Proteins c-fos - metabolism; Rats; Rats, Sprague-Dawley; Saccharin - administration & dosage; Tyrosine 3-Monooxygenase - metabolism; Ventral tegmental area; Ventral Tegmental Area - metabolism; Water - administration & dosage
• ISSN: 0361-9230; 1873-2747
• DOI: 10.1016/j.brainresbull.2014.11.002

Highlights • Corn oil, glucose, fructose, but not saccharin consumption activated c-Fos. • Ventral tegmental area and medial prefrontal cortex c-Fos increased after corn oil. • Corn oil and glucose increased dorsal striatum, amygdala and accumbens core c-Fos. • Fructose increased dorsal striatum, amygdala and infralimbic frontal cortex c-Fos. • The accumbens shell was not significantly activated by any nutrient.