Parenchymal lung changes on computed tomography after stereotactic radiotherapy using high dose rate flattening filter free beams

Abstract Flattening filter free (FFF) beams allow fast delivery of stereotactic radiotherapy. To evaluate biological effects of FFF in lung, we compared parenchymal changes after FFF and non-FFF stereotactic volumetric modulated arc therapy. Standardized multi-observer consensus evaluation of follow...

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Bibliographic Details
Published in:Radiotherapy and oncology 2015-03, Vol.114 (3), p.357-360
Main Authors: Dahele, Max, van Sörnsen de Koste, John R, van de Ven, Peter M, Spoelstra, Femke, Slotman, Ben, Senan, Suresh
Format: Article
Language:English
Subjects:
Aged
Female
Filtration
Follow up
Hematology, Oncology and Palliative Medicine
Humans
Imaging, Three-Dimensional
Lung - diagnostic imaging
Lung cancer
Lung changes
Lung Neoplasms - radiotherapy
Male
Radiotherapy Planning, Computer-Assisted - methods
Radiotherapy, Intensity-Modulated - methods
Stereotactic radiotherapy
Tomography, X-Ray Computed
Toxicity
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Summary:Abstract Flattening filter free (FFF) beams allow fast delivery of stereotactic radiotherapy. To evaluate biological effects of FFF in lung, we compared parenchymal changes after FFF and non-FFF stereotactic volumetric modulated arc therapy. Standardized multi-observer consensus evaluation of follow-up CT scans revealed no major differences between FFF and non-FFF.
ISSN:0167-8140
1879-0887
DOI:10.1016/j.radonc.2015.02.012