White blood cells levels and PCOS: direct and indirect relationship with obesity and insulin resistance, but not with hyperandogenemia

OBJECTIVE: To study white blood cells count (WBC) in women suffering from PCOS and compare these results with age and BMI-matched healthy women. The specific aim of this study was to assess the possible correlations of WBC with the major components of PCOS, obesity, insulin resistance and hyperandro...

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Bibliographic Details
Published in:Hormones (Athens, Greece) Greece), 2015-01, Vol.14 (1), p.91-100
Main Authors: Papalou, Olga, Livadas, Sarantis, Karachalios, Athanasios, Tolia, Nikoleta, Kokkoris, Panayiotis, Tripolitakis, Konstantinos, Diamanti-Kandarakis, Evanthia
Format: Article
Language:English
Subjects:
Adult
Body Mass Index
Endocrinology
Female
Humans
Hyperandrogenism - blood
Insulin Resistance - physiology
Leukocyte Count
Medicine
Medicine & Public Health
Metabolic Diseases
Obesity - blood
Polycystic Ovary Syndrome - blood
Research Paper
Young Adult
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Summary:OBJECTIVE: To study white blood cells count (WBC) in women suffering from PCOS and compare these results with age and BMI-matched healthy women. The specific aim of this study was to assess the possible correlations of WBC with the major components of PCOS, obesity, insulin resistance and hyperandrogenism. DESIGN: Anthropometrical, metabolic and hormonal data were analyzed from 203 women with PCOS (NIH criteria) and 76 age-matched controls. RESULTS: In the total population studied (N=279), WBC was significantly higher (P=0.003) in the PCOS group compared with age-matched healthy women and was positively correlated with BMI (r=0.461, p
ISSN:1109-3099
2520-8721
DOI:10.14310/horm.2002.1563