Evaluation of suspected soft tissue lesion in the prostate bed after radical prostatectomy using 3T multiparametric magnetic resonance imaging

To investigate the usefulness of multiparametric MR imaging (mp-MRI) at 3T for evaluating suspected soft tissue lesion in the prostate bed after radical prostatectomy (RP). Forty-three patients with biochemical recurrence (BCR) who received RP underwent mp-MRI at 3T with a phased-array coil, includi...

Full description

Saved in:
Bibliographic Details
Published in:Magnetic resonance imaging 2015-05, Vol.33 (4), p.407-412
Main Authors: Cha, Dongik, Kim, Chan Kyo, Park, Sung Yoon, Park, Jung Jae, Park, Byung Kwan
Format: Article
Language:English
Subjects:
Aged
Humans
Image Enhancement - methods
Image Interpretation, Computer-Assisted - methods
Local neoplasm recurrence
Magnetic resonance imaging
Magnetic Resonance Imaging - methods
Male
Middle Aged
Multimodal Imaging - methods
Multiparametric MRI
Neoplasm Recurrence, Local - pathology
Neoplasm Recurrence, Local - prevention & control
Neoplasm, Residual
Prostate cancer
Prostatectomy
Prostatic Neoplasms - pathology
Prostatic Neoplasms - surgery
Reproducibility of Results
Retrospective Studies
Sensitivity and Specificity
Treatment Outcome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To investigate the usefulness of multiparametric MR imaging (mp-MRI) at 3T for evaluating suspected soft tissue lesion in the prostate bed after radical prostatectomy (RP). Forty-three patients with biochemical recurrence (BCR) who received RP underwent mp-MRI at 3T with a phased-array coil, including T2-weighted imaging (T2WI), diffusion-weighted imaging (DWI) and dynamic contrast-enhanced imaging (DCE-MRI) and were enrolled in this study. All patients with BCR had a suspected soft tissue lesion in the prostate bed, followed by transrectal ultrasound-guided biopsy. As a control group, 14 consecutive patients without BCR who received RP were also enrolled. Two experienced radiologists independently analyzed four different imaging datasets. For predicting local recurrence, the specificity, accuracy and area under the curve for both readers were significantly greater on all combined imaging datasets than on T2WI alone (P0.05), except for combined T2WI and DWI. Inter-reader agreements for the four different imaging datasets were moderate. DCE-MRI or DWI in combination with T2WI at 3T with a phased-array coil appears to be more useful than T2WI alone in evaluating suspected soft tissue lesion of the prostate bed after RP.
ISSN:0730-725X
1873-5894
DOI:10.1016/j.mri.2014.12.003