Neurologic Symptom Severity after a Recent Noncardioembolic Stroke and Recurrent Vascular Risk

Background There is a well-established relation of symptom severity with functional status and mortality after an index stroke. However, little is known about the impact of symptom severity of a recent index stroke on risk of recurrent vascular events. Methods We reviewed the data set of a multicent...

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Bibliographic Details
Published in:Journal of stroke and cerebrovascular diseases 2015-05, Vol.24 (5), p.1032-1037
Main Authors: Park, Jong-Ho, MD, PhD, Ovbiagele, Bruce, MD, MSc, MAS
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Aspirin - administration & dosage
Cardiovascular
Coronary Artery Disease - complications
Double-Blind Method
Female
Fibrinolytic Agents - administration & dosage
Humans
ischemic stroke
Longitudinal Studies
Male
Middle Aged
National Institutes of Health Stroke Scale
Nervous System Diseases - etiology
Neurology
Predictive Value of Tests
Proportional Hazards Models
risk
Risk Factors
Severity of Illness Index
Stroke - complications
Stroke - prevention & control
Time Factors
vascular events
Vitamins - administration & dosage
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Summary:Background There is a well-established relation of symptom severity with functional status and mortality after an index stroke. However, little is known about the impact of symptom severity of a recent index stroke on risk of recurrent vascular events. Methods We reviewed the data set of a multicenter trial involving 3680 recent noncardioembolic stroke patients aged 35 years or older and followed for 2 years. Independent associations of stroke severity (as measured by National Institutes of Health Stroke Scale [NIHSS] score) with recurrent stroke (primary outcome) and stroke/coronary heart disease (CHD)/vascular death (secondary outcome) were analyzed. NIHSS score was analyzed as a dichotomous (
ISSN:1052-3057
1532-8511
DOI:10.1016/j.jstrokecerebrovasdis.2014.12.033