Glial fibrillary acidic protein: The component of iintermediate filaments in the vertebrate brain astrocytes

Glial fibrillary acidic protein (GFAP) refers to the type III intermediate filament proteins and is an essential component of the cytoskeleton in astrocytes of all vertebrates. This review presents current data on the molecular organization of GFAP in a comparative aspect. The results of most releva...

Full description

Saved in:
Bibliographic Details
Published in:Journal of evolutionary biochemistry and physiology 2015, Vol.51 (1), p.1-10
Main Authors: Sukhorukova, E. G., Korzhevskii, D. E., Alekseeva, O. S.
Format: Article
Language:English
Subjects:
Animal Physiology
Biochemistry
Biomedical and Life Sciences
Brain
Cytoskeleton
Evolutionary Biology
Life Sciences
Neurobiology
Neurological disorders
Proteins
Reviews
Vertebrates
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c415t-37696f025c878db6ff63fb89e05922e38a3a5f1de83f2ed35ce443e3e215034d3
cites cdi_FETCH-LOGICAL-c415t-37696f025c878db6ff63fb89e05922e38a3a5f1de83f2ed35ce443e3e215034d3
container_end_page 10
container_issue 1
container_start_page 1
container_title Journal of evolutionary biochemistry and physiology
container_volume 51
creator Sukhorukova, E. G.
Korzhevskii, D. E.
Alekseeva, O. S.
description Glial fibrillary acidic protein (GFAP) refers to the type III intermediate filament proteins and is an essential component of the cytoskeleton in astrocytes of all vertebrates. This review presents current data on the molecular organization of GFAP in a comparative aspect. The results of most relevant studies using immunocytochemical labeling of the protein are summarized. The data on the changes in expression of GFAP in Alexander disease caused by the primary pathology of astrocytes are presented.
doi_str_mv 10.1134/S0022093015010019
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1676346032</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3647501501</sourcerecordid><originalsourceid>FETCH-LOGICAL-c415t-37696f025c878db6ff63fb89e05922e38a3a5f1de83f2ed35ce443e3e215034d3</originalsourceid><addsrcrecordid>eNp1kE9LAzEQxYMoWKsfwFvAi5fVyZ9Nd71J0SoIHqznJc1ONGU3W5NU6Lc3Sz2I4mUC835vyHuEnDO4YkzI6xcAzqEWwEpgAKw-IBOmoCoEB35IJqNcjPoxOYlxDQB1JeWEdIvO6Y5atwqu63TYUW1c6wzdhCGh8zd0-Y7UDP1m8OgTHSx1zicMPbZOJ8zOTvdZidR5mjL7iSHhKoxannmpYwqD2SWMp-TI6i7i2fc7Ja_3d8v5Q_H0vHic3z4VRrIyFWKmamWBl6aaVe1KWauEXVU1QllzjqLSQpeWtVgJy7EVpUEpBQrkObyQrZiSy_3dHOJjizE1vYsGcz6PwzY2TM2UkAoEz-jFL3Q9bIPPvxspqJmsSpYptqdMGGIMaJtNcH1uq2HQjP03f_rPHr73xMz6Nww_Lv9r-gKHmIdV</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1670914851</pqid></control><display><type>article</type><title>Glial fibrillary acidic protein: The component of iintermediate filaments in the vertebrate brain astrocytes</title><source>Springer Nature</source><creator>Sukhorukova, E. G. ; Korzhevskii, D. E. ; Alekseeva, O. S.</creator><creatorcontrib>Sukhorukova, E. G. ; Korzhevskii, D. E. ; Alekseeva, O. S.</creatorcontrib><description>Glial fibrillary acidic protein (GFAP) refers to the type III intermediate filament proteins and is an essential component of the cytoskeleton in astrocytes of all vertebrates. This review presents current data on the molecular organization of GFAP in a comparative aspect. The results of most relevant studies using immunocytochemical labeling of the protein are summarized. The data on the changes in expression of GFAP in Alexander disease caused by the primary pathology of astrocytes are presented.</description><identifier>ISSN: 0022-0930</identifier><identifier>EISSN: 1608-3202</identifier><identifier>DOI: 10.1134/S0022093015010019</identifier><language>eng</language><publisher>Moscow: Pleiades Publishing</publisher><subject>Animal Physiology ; Biochemistry ; Biomedical and Life Sciences ; Brain ; Cytoskeleton ; Evolutionary Biology ; Life Sciences ; Neurobiology ; Neurological disorders ; Proteins ; Reviews ; Vertebrates</subject><ispartof>Journal of evolutionary biochemistry and physiology, 2015, Vol.51 (1), p.1-10</ispartof><rights>Pleiades Publishing, Ltd. 2015</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c415t-37696f025c878db6ff63fb89e05922e38a3a5f1de83f2ed35ce443e3e215034d3</citedby><cites>FETCH-LOGICAL-c415t-37696f025c878db6ff63fb89e05922e38a3a5f1de83f2ed35ce443e3e215034d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Sukhorukova, E. G.</creatorcontrib><creatorcontrib>Korzhevskii, D. E.</creatorcontrib><creatorcontrib>Alekseeva, O. S.</creatorcontrib><title>Glial fibrillary acidic protein: The component of iintermediate filaments in the vertebrate brain astrocytes</title><title>Journal of evolutionary biochemistry and physiology</title><addtitle>J Evol Biochem Phys</addtitle><description>Glial fibrillary acidic protein (GFAP) refers to the type III intermediate filament proteins and is an essential component of the cytoskeleton in astrocytes of all vertebrates. This review presents current data on the molecular organization of GFAP in a comparative aspect. The results of most relevant studies using immunocytochemical labeling of the protein are summarized. The data on the changes in expression of GFAP in Alexander disease caused by the primary pathology of astrocytes are presented.</description><subject>Animal Physiology</subject><subject>Biochemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Brain</subject><subject>Cytoskeleton</subject><subject>Evolutionary Biology</subject><subject>Life Sciences</subject><subject>Neurobiology</subject><subject>Neurological disorders</subject><subject>Proteins</subject><subject>Reviews</subject><subject>Vertebrates</subject><issn>0022-0930</issn><issn>1608-3202</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNp1kE9LAzEQxYMoWKsfwFvAi5fVyZ9Nd71J0SoIHqznJc1ONGU3W5NU6Lc3Sz2I4mUC835vyHuEnDO4YkzI6xcAzqEWwEpgAKw-IBOmoCoEB35IJqNcjPoxOYlxDQB1JeWEdIvO6Y5atwqu63TYUW1c6wzdhCGh8zd0-Y7UDP1m8OgTHSx1zicMPbZOJ8zOTvdZidR5mjL7iSHhKoxannmpYwqD2SWMp-TI6i7i2fc7Ja_3d8v5Q_H0vHic3z4VRrIyFWKmamWBl6aaVe1KWauEXVU1QllzjqLSQpeWtVgJy7EVpUEpBQrkObyQrZiSy_3dHOJjizE1vYsGcz6PwzY2TM2UkAoEz-jFL3Q9bIPPvxspqJmsSpYptqdMGGIMaJtNcH1uq2HQjP03f_rPHr73xMz6Nww_Lv9r-gKHmIdV</recordid><startdate>2015</startdate><enddate>2015</enddate><creator>Sukhorukova, E. G.</creator><creator>Korzhevskii, D. E.</creator><creator>Alekseeva, O. S.</creator><general>Pleiades Publishing</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QG</scope><scope>7QR</scope><scope>7SS</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88I</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M2P</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope></search><sort><creationdate>2015</creationdate><title>Glial fibrillary acidic protein: The component of iintermediate filaments in the vertebrate brain astrocytes</title><author>Sukhorukova, E. G. ; Korzhevskii, D. E. ; Alekseeva, O. S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c415t-37696f025c878db6ff63fb89e05922e38a3a5f1de83f2ed35ce443e3e215034d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Animal Physiology</topic><topic>Biochemistry</topic><topic>Biomedical and Life Sciences</topic><topic>Brain</topic><topic>Cytoskeleton</topic><topic>Evolutionary Biology</topic><topic>Life Sciences</topic><topic>Neurobiology</topic><topic>Neurological disorders</topic><topic>Proteins</topic><topic>Reviews</topic><topic>Vertebrates</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sukhorukova, E. G.</creatorcontrib><creatorcontrib>Korzhevskii, D. E.</creatorcontrib><creatorcontrib>Alekseeva, O. S.</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Neurosciences Abstracts</collection><collection>Health &amp; Medicine (ProQuest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>ProQuest Science Journals</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><jtitle>Journal of evolutionary biochemistry and physiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sukhorukova, E. G.</au><au>Korzhevskii, D. E.</au><au>Alekseeva, O. S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Glial fibrillary acidic protein: The component of iintermediate filaments in the vertebrate brain astrocytes</atitle><jtitle>Journal of evolutionary biochemistry and physiology</jtitle><stitle>J Evol Biochem Phys</stitle><date>2015</date><risdate>2015</risdate><volume>51</volume><issue>1</issue><spage>1</spage><epage>10</epage><pages>1-10</pages><issn>0022-0930</issn><eissn>1608-3202</eissn><abstract>Glial fibrillary acidic protein (GFAP) refers to the type III intermediate filament proteins and is an essential component of the cytoskeleton in astrocytes of all vertebrates. This review presents current data on the molecular organization of GFAP in a comparative aspect. The results of most relevant studies using immunocytochemical labeling of the protein are summarized. The data on the changes in expression of GFAP in Alexander disease caused by the primary pathology of astrocytes are presented.</abstract><cop>Moscow</cop><pub>Pleiades Publishing</pub><doi>10.1134/S0022093015010019</doi><tpages>10</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0022-0930
ispartof Journal of evolutionary biochemistry and physiology, 2015, Vol.51 (1), p.1-10
issn 0022-0930
1608-3202
language eng
recordid cdi_proquest_miscellaneous_1676346032
source Springer Nature
subjects Animal Physiology
Biochemistry
Biomedical and Life Sciences
Brain
Cytoskeleton
Evolutionary Biology
Life Sciences
Neurobiology
Neurological disorders
Proteins
Reviews
Vertebrates
title Glial fibrillary acidic protein: The component of iintermediate filaments in the vertebrate brain astrocytes
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T18%3A25%3A18IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Glial%20fibrillary%20acidic%20protein:%20The%20component%20of%20iintermediate%20filaments%20in%20the%20vertebrate%20brain%20astrocytes&rft.jtitle=Journal%20of%20evolutionary%20biochemistry%20and%20physiology&rft.au=Sukhorukova,%20E.%20G.&rft.date=2015&rft.volume=51&rft.issue=1&rft.spage=1&rft.epage=10&rft.pages=1-10&rft.issn=0022-0930&rft.eissn=1608-3202&rft_id=info:doi/10.1134/S0022093015010019&rft_dat=%3Cproquest_cross%3E3647501501%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c415t-37696f025c878db6ff63fb89e05922e38a3a5f1de83f2ed35ce443e3e215034d3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1670914851&rft_id=info:pmid/&rfr_iscdi=true