Rosuvastatin Enhances the Catabolism of LDL apoB-100 in Subjects with Combined Hyperlipidemia in a Dose Dependent Manner

• Published in: Lipids 2015-05, Vol.50 (5), p.447-458
• Main Authors: Le, Ngoc-Anh, Diffenderfer, Margaret R., Thongtang, Nuntakorn, Ooi, Esther M. M., Barrett, P. Hugh R., Horvath, Katalin V., Dolnikowski, Gregory G., Asztalos, Bela F., Schaefer, Ernst J., Brown, W. Virgil
• Format: Article
• Language: English
• Subjects: Apolipoprotein B-100 - metabolism; Biomedical and Life Sciences; Cholesterol; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gas chromatography; HDL subpopulations; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage; Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology; Hyperlipidemia, Familial Combined - drug therapy; Hyperlipidemia, Familial Combined - metabolism; Kinetics; Life Sciences; Lipidology; Lipoprotein kinetics; Lipoproteins, LDL - metabolism; Male; Mass spectrometry; Medical Biochemistry; Medicinal Chemistry; Metabolism; Microbial Genetics and Genomics; Middle Aged; Neurochemistry; Nutrition; Original Article; Plasma sterols; Rosuvastatin Calcium - administration & dosage; Rosuvastatin Calcium - pharmacology; Stable isotopes; Statins; Triglycerides - metabolism
• ISSN: 0024-4201; 1558-9307
• DOI: 10.1007/s11745-015-4005-0

Dose-associated effects of rosuvastatin on the metabolism of apolipoprotein (apo) B-100 in triacylglycerol rich lipoprotein (TRL, d