Small Bowel Bacterial Overgrowth Associated with Persistence of Abdominal Symptoms in Children Treated with a Proton Pump Inhibitor

Small bowel bacterial overgrowth (SBBO) was diagnosed in 22.5% of 40 children treated for 3 months with a proton pump inhibitor (PPI). Compared with those without SBBO, children with SBBO had higher frequency of abdominal pain, bloating, eructation, and flatulence. Patients with gastrointestinal sym...

Full description

Saved in:
Bibliographic Details
Published in:The Journal of pediatrics 2015-05, Vol.166 (5), p.1310-1312.e1
Main Authors: Sieczkowska, Agnieszka, MD, Landowski, Piotr, MD, PhD, Zagozdzon, Pawel, MD, PhD, Kaminska, Barbara, MD, PhD, Lifschitz, Carlos, MD
Format: Article
Language:English
Subjects:
Abdominal Pain - diagnosis
Adolescent
Breath Tests
Child
Child, Preschool
Female
Flatulence
Gastrointestinal Diseases
Humans
Hydrogen - chemistry
Intestine, Small - microbiology
Male
Microbiota
Pediatrics
Prospective Studies
Proton Pump Inhibitors - adverse effects
Proton Pump Inhibitors - therapeutic use
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Small bowel bacterial overgrowth (SBBO) was diagnosed in 22.5% of 40 children treated for 3 months with a proton pump inhibitor (PPI). Compared with those without SBBO, children with SBBO had higher frequency of abdominal pain, bloating, eructation, and flatulence. Patients with gastrointestinal symptoms after PPI treatment should be evaluated for SBBO rather than empirically prolonging PPI therapy.
ISSN:0022-3476
1097-6833
DOI:10.1016/j.jpeds.2015.01.004