Post-treatment control of HIV infection

Antiretroviral therapy (ART) for HIV is not a cure. However, recent studies suggest that ART, initiated early during primary infection, may induce post-treatment control (PTC) of HIV infection with HIV RNA maintained at

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Bibliographic Details
Published in:Proceedings of the National Academy of Sciences - PNAS 2015-04, Vol.112 (17), p.5467-5472
Main Authors: Conway, Jessica M., Perelson, Alan S.
Format: Article
Language:English
Subjects:
Adaptive Immunity
Antiretroviral drugs
BASIC BIOLOGICAL SCIENCES
Biological Sciences
CD8-Positive T-Lymphocytes - immunology
Disease control
Drug therapy
Female
HIV
HIV Infections - immunology
HIV Infections - prevention & control
HIV latency
HIV-1 - physiology
Human immunodeficiency virus
Humans
immune exhaustion
Immunity (Disease)
mathematical modeling
Mathematical models
Models, Immunological
Physical Sciences
post-treatment control
Virus Latency - immunology
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Description
Summary:Antiretroviral therapy (ART) for HIV is not a cure. However, recent studies suggest that ART, initiated early during primary infection, may induce post-treatment control (PTC) of HIV infection with HIV RNA maintained at
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.1419162112