Changes in the metabolic profile of pregnant ewes to an acute feed restriction in late gestation

AIM: To detect early changes in the metabolic profile of pregnant ewes subject to acute feed restriction at 130 days of gestation, and to establish indicators of risk for ovine pregnancy toxaemia (OPT) for diagnostic purposes. METHODS: Twenty Corriedale ewes with known mating dates, carrying a singl...

Full description

Saved in:
Bibliographic Details
Published in:New Zealand veterinary journal 2015-05, Vol.63 (3), p.141-146
Main Authors: Cal-Pereyra, L, Benech, A, González-Montaña, JR, Acosta-Dibarrat, J, Da Silva, S, Martín, A
Format: Article
Language:English
Subjects:
3-Hydroxybutyric Acid - blood
Animals
blood
Blood Glucose
Corriedale
cortisol
drinking water
Energy Metabolism - physiology
ewes
Fatty Acids, Nonesterified - blood
Female
Food Deprivation - physiology
free fatty acids
glucose
grinding
head
mastication
meadows
non-esterified fatty acids
Ovine pregnancy toxaemia
Pregnancy
pregnancy toxemia
restricted feeding
risk
sheep
Sheep - blood
Sheep - physiology
Sheep - urine
tachypnea
teeth
Time Factors
ß-hydroxybuthyrate
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:AIM: To detect early changes in the metabolic profile of pregnant ewes subject to acute feed restriction at 130 days of gestation, and to establish indicators of risk for ovine pregnancy toxaemia (OPT) for diagnostic purposes. METHODS: Twenty Corriedale ewes with known mating dates, carrying a single fetus, were used. Ewes were maintained on meadow grasslands and at 130 days of gestation were randomly divided in two groups of 10 ewes. The control group had ad libitum access to pasture. Ewes in the restricted group were subjected to an acute feed restriction for a maximum of 144 hours (6 days), with free access to water. From the start (0 hours) until the end of feed restriction, blood samples were collected from all ewes to monitor concentrations of cortisol, non-esterified fatty acids (NEFA), ß-hydroxybutyrate (BOHB) daily, and glucose in plasma every 6 hours; urinary pH was also measured. Every 6 hours the food restricted ewes were observed to detect clinical signs of OPT e.g. apathy, grinding teeth, empty chewing movements, head leaning against the wall, tachypnea and not drinking water. RESULTS: In food-restricted ewes, concentrations of glucose decreased and differed from control ewes from 54 to 90 hours (p
ISSN:1176-0710
0048-0169
1176-0710
DOI:10.1080/00480169.2014.971083