Imaging of extraosseous intracranial and intraspinal multiple myeloma, including central nervous system involvement

Abstract Involvement of the central nervous system by multiple myeloma is rare and has a very poor prognosis. Magnetic resonance imaging of the head and spine plays an important role in diagnosing central nervous system involvement with multiple myeloma. We retrospectively analyzed the imaging featu...

Full description

Saved in:
Bibliographic Details
Published in:Clinical imaging 2015-03, Vol.39 (2), p.213-219
Main Authors: Shpilberg, Katya A, Esses, Steven J, Fowkes, Mary E, Chari, Ajai, Sacher, Michael, Naidich, Thomas P
Format: Article
Language:English
Subjects:
Aged
Bone marrow
Brain - pathology
Brain MRI
Central nervous system
Central Nervous System Neoplasms - pathology
CNS involvement
Extraosseous myeloma
Female
Humans
Imaging
Lesions
Lumbar Vertebrae
Magnetic Resonance Imaging
Male
Medical imaging
Medical treatment
Middle Aged
Multiple myeloma
Multiple Myeloma - pathology
Nerves
NMR
Nuclear magnetic resonance
Prognosis
Radiology
Retrospective Studies
Spinal Cord - pathology
Spine
Spine MRI
Thoracic Vertebrae
Transplants & implants
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Involvement of the central nervous system by multiple myeloma is rare and has a very poor prognosis. Magnetic resonance imaging of the head and spine plays an important role in diagnosing central nervous system involvement with multiple myeloma. We retrospectively analyzed the imaging features of pathology-proven extraosseous intracranial and intraspinal multiple myeloma from 2002 to 2013. The most common imaging manifestations were extraaxial nonosseous spinal lesions, cranial nerve involvement, and intracranial extraaxial nonosseous lesions. Different sites in the central nervous system may be affected by multiple myeloma, often simultaneously, producing a variety of imaging appearances.
ISSN:0899-7071
1873-4499
DOI:10.1016/j.clinimag.2014.11.017