Nanomolar simultaneous determination of epinephrine and acetaminophen on a glassy carbon electrode coated with a novel Mg–Al layered double hydroxide–nickel hydroxide nanoparticles–multi-walled carbon nanotubes composite

The present work demonstrates that the simultaneous determination of epinephrine (EPI) and acetaminophen (ACT) can be performed using a glassy carbon electrode (GCE) modified with a novel multi-walled carbon nanotubes (MWCNTs), nickel hydroxide nanoparticles (NHNPs) and Mg–Al layered double hydroxid...

Full description

Saved in:
Bibliographic Details
Published in:Analytical methods 2015-01, Vol.7 (6), p.2469-2478
Main Authors: Babaei, Ali, Afrasiabi, Mohammad, Azimi, Gholamhassan
Format: Article
Language:English
Subjects:
Electrodes
Epinephrine
Glassy carbon
Hydroxides
Magnesium
Nanostructure
Nickel
Voltammetry
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The present work demonstrates that the simultaneous determination of epinephrine (EPI) and acetaminophen (ACT) can be performed using a glassy carbon electrode (GCE) modified with a novel multi-walled carbon nanotubes (MWCNTs), nickel hydroxide nanoparticles (NHNPs) and Mg–Al layered double hydroxide (LDH) composite (MWCNTs–NHNPs–LDH/GCE). The electro-oxidations of EPI and ACT were investigated using cyclic voltammetry (CV), differential pulse voltammetry (DPV) and chronoamperometry (CA) methods. Under optimum conditions, DPV indicated linear relationships between oxidation peak current and EPI and ACT concentrations in the ranges of 0.04–60 μM and 0.02–40 μM with detection limits of 11 and 5 nM, respectively. The proposed method was successfully applied to the determination of these compounds in human urine and blood serum samples.
ISSN:1759-9660
1759-9679
DOI:10.1039/C4AY02406K