Prevalence and Prognostic Role of Right Ventricular Involvement in Stress-Induced Cardiomyopathy

Abstract Background Stress-induced cardiomyopathy (SCM) is a reversible cardiomyopathy observed in patients without significant coronary disease. The aim of this study was to assess the incidence and clinical significance of right ventricular (RV) involvement in SCM. Methods and Results We retrospec...

Full description

Saved in:
Bibliographic Details
Published in:Journal of cardiac failure 2015-05, Vol.21 (5), p.419-425
Main Authors: Finocchiaro, Gherardo, MD, Kobayashi, Yukari, MD, Magavern, Emma, BA, MD, Zhou, Jessica Q., MD, Ashley, Euan, MD, DPhil, Sinagra, Gianfranco, MD, Schnittger, Ingela, MD, Knowles, Joshua W., MD, PhD, Fearon, William F., MD, Haddad, Francois, MD, Tremmel, Jennifer A., MD, MS
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Cardiovascular
Cohort Studies
echocardiography
Female
Humans
Male
Middle Aged
Prevalence
Prognosis
Retrospective Studies
right ventricle
Stress cardiomyopathy
Stroke Volume - physiology
Takotsubo Cardiomyopathy - diagnosis
Takotsubo Cardiomyopathy - epidemiology
Takotsubo Cardiomyopathy - physiopathology
Ventricular Dysfunction, Right - diagnosis
Ventricular Dysfunction, Right - epidemiology
Ventricular Dysfunction, Right - physiopathology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Background Stress-induced cardiomyopathy (SCM) is a reversible cardiomyopathy observed in patients without significant coronary disease. The aim of this study was to assess the incidence and clinical significance of right ventricular (RV) involvement in SCM. Methods and Results We retrospectively analyzed echocardiograms from 40 consecutive patients who presented with SCM at Stanford University Medical Center from September 2000 to November 2010. The primary end point was overall mortality. RV involvement was observed in 20 patients (50%; global RV hypokinesia in 15 patients and focal RV apical akinesia in 5 patients). The independent correlates of RV involvement were older age (odds ratio [OR] 1.09, 95% confidence interval [CI] 1.02–1.7two, P  = .01) and LVEF (per 10% decrease: OR 3.60, CI 1.77–7.32; P  = .02). At a mean follow-up of 44 ± 32 months, 12 patients (30%) died (in-hospital death in 3 patients). At multivariate analysis, the presence of an RV fractional area change
ISSN:1071-9164
1532-8414
DOI:10.1016/j.cardfail.2015.02.001