First data from the German Lipoprotein Apheresis Registry (GLAR)

In recent years the Federal Joint Committee (G-BA), a paramount decision-making body of the German health care system challenged the approval of diagnostic and therapeutic procedures for regular reimbursement, including lipoprotein apheresis therapy. Years before an interdisciplinary German apheresi...

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Bibliographic Details
Published in:Atherosclerosis. Supplements 2015-05, Vol.18, p.41-44
Main Authors: Schettler, Volker J.J., Neumann, Class L., Peter, Christian, Zimmermann, Thomas, Julius, Ulrich, Roeseler, Eberhard, Heigl, Franz, Ramlow, Wolfgang, Blume, Helmut
Format: Article
Language:English
Subjects:
Biomarkers - blood
Blood Component Removal - methods
Cardiovascular Diseases - etiology
Cardiovascular Diseases - prevention & control
First data
Germany
Humans
Hyperlipoproteinemias - blood
Hyperlipoproteinemias - complications
Hyperlipoproteinemias - diagnosis
Hyperlipoproteinemias - therapy
Lipoprotein apheresis
Lipoprotein Apheresis Registry
Lipoproteins - blood
Registries
Risk Factors
Time Factors
Treatment Outcome
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Summary:In recent years the Federal Joint Committee (G-BA), a paramount decision-making body of the German health care system challenged the approval of diagnostic and therapeutic procedures for regular reimbursement, including lipoprotein apheresis therapy. Years before an interdisciplinary German apheresis working group, established by members of both German Societies of Nephrology (Verband Deutsche Nierenzentren (VDN), Deutsche Gesellschaft für Nephrologie (DGfN)), initiated a revision of the indication of lipoprotein apheresis therapy according to current guidelines and recommendations for the treatment of lipid disorders. This working group was convinced, that data derived from a registry would support lipoprotein apheresis as a therapy for severe hyperlipidemic patients suffering from progressive cardiovascular diseases. In 2009 the working group established the indication for lipoprotein apheresis with respect to current cardiovascular guidelines and scientific knowledge for the registry, which are in line with the reimbursement guidelines. In 2011 financing by sponsors was secured and an internet-based registry was created. A pilot project with 5 apheresis centers finished in 2012 – since then the registry is available to all German apheresis centers. There has been consensus between the medical societies and health care carriers regarding the need for a German Lipoprotein Apheresis Registry (GLAR). The launch of this registry complies with requirements of the Federal Joint Committee (G-BA). Complementing the Pro(a)LiFe-Study, first data from GLAR support the safety of the different apheresis treatment procedures. In addition these first data suggest, with respect to the results of Pro(a)LiFe-Study, effectiveness in preventing cardiovascular progression as well. Here, further data are needed to statistically substantiate these early findings.
ISSN:1567-5688
1878-5050
DOI:10.1016/j.atherosclerosissup.2015.02.006