Opportunistic infections and profound CD8 super(+) T lymphocytopenia in mixed connective tissue disease

Although > 50 genetically determined immunodeficiency syndromes have been reported over the past decades, defects in immunity due to CD4 super(+) T lymphocytopenia were considered rare until the discovery of AIDS. Recently, 47 patients were identified as having idiopathic CD4 super(+) T lymphocyt...

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Bibliographic Details
Published in:The Journal of infectious diseases 1993-01, Vol.168 (5), p.1333-1334
Main Authors: Jansen, TLThA, Janssen, M, Meijer, JWG, Van Nierop, MAMF, Katchaki, J N, Van Dijk, TJA, Weber, J, Werre, J M
Format: Article
Language:English
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Summary:Although > 50 genetically determined immunodeficiency syndromes have been reported over the past decades, defects in immunity due to CD4 super(+) T lymphocytopenia were considered rare until the discovery of AIDS. Recently, 47 patients were identified as having idiopathic CD4 super(+) T lymphocytopenia with susceptibility to opportunistic infections. We studied a young woman with an AIDS-like syndrome who had several opportunistic infections in combination with a persistent CD8 super(+) T lymphocytopenia and recurrent CD4 super(+) T lymphocytopenia.
ISSN:0022-1899