Non-motor symptoms in an Indian cohort of Parkinson's disease patients and correlation of progression of non-motor symptoms with motor worsening

To document the frequency and prevalence of non-motor symptoms (NMS) in an Indian cohort of Parkinson's disease (PD) patients. To validate the non-motor score scale (NMSS) in an Indian cohort of PD patients for recording NMS of the disease, to study the prevalence and frequency of NMS in Indian...

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Bibliographic Details
Published in:Neurology India 2015-03, Vol.63 (2), p.166-174
Main Authors: Ravan, Amruta, Ahmad, Faiz M H, Chabria, Sonali, Gadhari, Mangesh, Sankhla, Charulata Savant
Format: Article
Language:English
Subjects:
Age
Behavior
Development and progression
Diagnosis
Memory
Mortality
Older people
Parkinson disease
Parkinsons disease
Patients
Quality of life
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Summary:To document the frequency and prevalence of non-motor symptoms (NMS) in an Indian cohort of Parkinson's disease (PD) patients. To validate the non-motor score scale (NMSS) in an Indian cohort of PD patients for recording NMS of the disease, to study the prevalence and frequency of NMS in Indian PD patients using the NMSS, and to compare the progression of NMS with motor worsening. Conclusion and Results: This was a cross-sectional, single-center, open-label, one point in time evaluation study conducted from 2009 to 2011. It validated the NMSS scale in an Indian population. The study has profiled the prevalence and pattern of NMS in an Indian cohort of PD patients. Comparison of NMS scale scores with the Unified PD Rating Scale motor scores demonstrated a correlation between non-motor and motor symptoms in the disease progression, particularly of manifestations related to the cognitive decline, memory disturbances, urinary incontinence and smell.
ISSN:0028-3886
1998-4022
DOI:10.4103/0028-3886.156276