How Recent Data Have Impacted the Treatment of Internal Carotid Artery Stenosis

Abstract Carotid atherosclerosis accounts for approximately 10% of ischemic stroke cases. Multifaceted medical therapy reduces the risk of stroke in patients with carotid stenosis. Revascularization with endarterectomy or stenting can benefit select patients. In recent years, new information has bee...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2015-03, Vol.65 (11), p.1134-1143
Main Authors: Chaturvedi, Seemant, MD, Sacco, Ralph L., MD
Format: Article
Language:English
Subjects:
Angioplasty
atherosclerosis
Cardiology
Cardiovascular
Carotid Artery, Internal
Carotid Stenosis - complications
Carotid Stenosis - therapy
carotid stenosis
Cholesterol
endarterectomy
Endarterectomy, Carotid
Heart attacks
Humans
Internal Medicine
Older people
stenting
Stents
Stroke
Stroke - etiology
Stroke - prevention & control
stroke prevention
stroke risk
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Description
Summary:Abstract Carotid atherosclerosis accounts for approximately 10% of ischemic stroke cases. Multifaceted medical therapy reduces the risk of stroke in patients with carotid stenosis. Revascularization with endarterectomy or stenting can benefit select patients. In recent years, new information has been obtained regarding optimal selection of revascularization candidates. In addition, new concepts have been formulated regarding the relationship between carotid stenosis and vascular cognitive impairment. Finally, the declining rate of stroke with improved medical therapy has led to the launch of new clinical trials to determine the contemporary risk/benefit ratio of revascularization relative to aggressive medical therapy.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2014.12.045