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How Recent Data Have Impacted the Treatment of Internal Carotid Artery Stenosis
Abstract Carotid atherosclerosis accounts for approximately 10% of ischemic stroke cases. Multifaceted medical therapy reduces the risk of stroke in patients with carotid stenosis. Revascularization with endarterectomy or stenting can benefit select patients. In recent years, new information has bee...
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Published in: | Journal of the American College of Cardiology 2015-03, Vol.65 (11), p.1134-1143 |
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container_title | Journal of the American College of Cardiology |
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creator | Chaturvedi, Seemant, MD Sacco, Ralph L., MD |
description | Abstract Carotid atherosclerosis accounts for approximately 10% of ischemic stroke cases. Multifaceted medical therapy reduces the risk of stroke in patients with carotid stenosis. Revascularization with endarterectomy or stenting can benefit select patients. In recent years, new information has been obtained regarding optimal selection of revascularization candidates. In addition, new concepts have been formulated regarding the relationship between carotid stenosis and vascular cognitive impairment. Finally, the declining rate of stroke with improved medical therapy has led to the launch of new clinical trials to determine the contemporary risk/benefit ratio of revascularization relative to aggressive medical therapy. |
doi_str_mv | 10.1016/j.jacc.2014.12.045 |
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Multifaceted medical therapy reduces the risk of stroke in patients with carotid stenosis. Revascularization with endarterectomy or stenting can benefit select patients. In recent years, new information has been obtained regarding optimal selection of revascularization candidates. In addition, new concepts have been formulated regarding the relationship between carotid stenosis and vascular cognitive impairment. Finally, the declining rate of stroke with improved medical therapy has led to the launch of new clinical trials to determine the contemporary risk/benefit ratio of revascularization relative to aggressive medical therapy.</description><identifier>ISSN: 0735-1097</identifier><identifier>EISSN: 1558-3597</identifier><identifier>DOI: 10.1016/j.jacc.2014.12.045</identifier><identifier>PMID: 25790886</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Angioplasty ; atherosclerosis ; Cardiology ; Cardiovascular ; Carotid Artery, Internal ; Carotid Stenosis - complications ; Carotid Stenosis - therapy ; carotid stenosis ; Cholesterol ; endarterectomy ; Endarterectomy, Carotid ; Heart attacks ; Humans ; Internal Medicine ; Older people ; stenting ; Stents ; Stroke ; Stroke - etiology ; Stroke - prevention & control ; stroke prevention ; stroke risk</subject><ispartof>Journal of the American College of Cardiology, 2015-03, Vol.65 (11), p.1134-1143</ispartof><rights>American College of Cardiology Foundation</rights><rights>2015 American College of Cardiology Foundation</rights><rights>Copyright © 2015 American College of Cardiology Foundation. 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Multifaceted medical therapy reduces the risk of stroke in patients with carotid stenosis. Revascularization with endarterectomy or stenting can benefit select patients. In recent years, new information has been obtained regarding optimal selection of revascularization candidates. In addition, new concepts have been formulated regarding the relationship between carotid stenosis and vascular cognitive impairment. Finally, the declining rate of stroke with improved medical therapy has led to the launch of new clinical trials to determine the contemporary risk/benefit ratio of revascularization relative to aggressive medical therapy.</description><subject>Angioplasty</subject><subject>atherosclerosis</subject><subject>Cardiology</subject><subject>Cardiovascular</subject><subject>Carotid Artery, Internal</subject><subject>Carotid Stenosis - complications</subject><subject>Carotid Stenosis - therapy</subject><subject>carotid stenosis</subject><subject>Cholesterol</subject><subject>endarterectomy</subject><subject>Endarterectomy, Carotid</subject><subject>Heart attacks</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Older people</subject><subject>stenting</subject><subject>Stents</subject><subject>Stroke</subject><subject>Stroke - etiology</subject><subject>Stroke - prevention & control</subject><subject>stroke prevention</subject><subject>stroke risk</subject><issn>0735-1097</issn><issn>1558-3597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNp9kVGL1DAQx4Mo3t7pF_BBAr740jpJm7QFEY7VcxcODrzzOcTJFFO77ZpkT_bbm7Knwj0IIYHw-w8zv2HslYBSgNDvhnKwiKUEUZdCllCrJ2wllGqLSnXNU7aCplKFgK45Y-cxDgCgW9E9Z2dSNR20rV6xm838i38hpCnxjzZZvrH3xLe7vcVEjqfvxO8C2bRbgLnn2ylRmOzI1zbMyTt-GfLHkd8mmubo4wv2rLdjpJcP7wX7evXpbr0prm8-b9eX1wXWVZcK2clG9440QS0Aoeop351TCvtauhZJAziVj0QnW3TOKo0IEiqttMbqgr091d2H-eeBYjI7H5HG0U40H6IRugXRAVQqo28eocN8WGZYKF3nRkSjMyVPFIY5xkC92Qe_s-FoBJhFtxnMotssuo2QJuvOodcPpQ_fduT-Rv74zcD7E0DZxb2nYCJ6mpCcD4TJuNn_v_6HR3Ec_eTRjj_oSPHfHCbmgLldFr7sWygAIZu2-g0eyaOy</recordid><startdate>20150324</startdate><enddate>20150324</enddate><creator>Chaturvedi, Seemant, MD</creator><creator>Sacco, Ralph L., MD</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20150324</creationdate><title>How Recent Data Have Impacted the Treatment of Internal Carotid Artery Stenosis</title><author>Chaturvedi, Seemant, MD ; Sacco, Ralph L., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c439t-29276fde6e0410c03fe0c09d55cf42d8ce600d50d52cd28cdda56cc02036566c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Angioplasty</topic><topic>atherosclerosis</topic><topic>Cardiology</topic><topic>Cardiovascular</topic><topic>Carotid Artery, Internal</topic><topic>Carotid Stenosis - complications</topic><topic>Carotid Stenosis - therapy</topic><topic>carotid stenosis</topic><topic>Cholesterol</topic><topic>endarterectomy</topic><topic>Endarterectomy, Carotid</topic><topic>Heart attacks</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Older people</topic><topic>stenting</topic><topic>Stents</topic><topic>Stroke</topic><topic>Stroke - etiology</topic><topic>Stroke - prevention & control</topic><topic>stroke prevention</topic><topic>stroke risk</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chaturvedi, Seemant, MD</creatorcontrib><creatorcontrib>Sacco, Ralph L., MD</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American College of Cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chaturvedi, Seemant, MD</au><au>Sacco, Ralph L., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>How Recent Data Have Impacted the Treatment of Internal Carotid Artery Stenosis</atitle><jtitle>Journal of the American College of Cardiology</jtitle><addtitle>J Am Coll Cardiol</addtitle><date>2015-03-24</date><risdate>2015</risdate><volume>65</volume><issue>11</issue><spage>1134</spage><epage>1143</epage><pages>1134-1143</pages><issn>0735-1097</issn><eissn>1558-3597</eissn><abstract>Abstract Carotid atherosclerosis accounts for approximately 10% of ischemic stroke cases. 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subjects | Angioplasty atherosclerosis Cardiology Cardiovascular Carotid Artery, Internal Carotid Stenosis - complications Carotid Stenosis - therapy carotid stenosis Cholesterol endarterectomy Endarterectomy, Carotid Heart attacks Humans Internal Medicine Older people stenting Stents Stroke Stroke - etiology Stroke - prevention & control stroke prevention stroke risk |
title | How Recent Data Have Impacted the Treatment of Internal Carotid Artery Stenosis |
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