Distribution, virulence-associated genes and antimicrobial resistance of Aeromonas isolates from diarrheal patients and water, China

Summary Objectives To determine the prevalence of Aeromonas infections in diarrheal patients, the distribution of virulence-associated genes and antibiotic resistance among different Aeromonas species in China. Methods We conducted continual active surveillance aimed on Aeromonas from diarrheal pati...

Full description

Saved in:
Bibliographic Details
Published in:The Journal of infection 2015-06, Vol.70 (6), p.600-608
Main Authors: Li, Fengjuan, Wang, Wenqing, Zhu, Zhaoqin, Chen, Aiping, Du, Pengcheng, Wang, Ruibai, Chen, Haili, Hu, Yunwen, Li, Jie, Kan, Biao, Wang, Duochun
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aeromonas - drug effects
Aeromonas - genetics
Aeromonas - isolation & purification
Aeromonas - pathogenicity
Aeromonas isolates
Aged
Aged, 80 and over
Anti-Infective Agents - pharmacology
Antimicrobial resistance
Bacterial Proteins - genetics
Child
Child, Preschool
China
China - epidemiology
Coinfection
Diarrhea - microbiology
Distribution
Drug Resistance, Bacterial
Feces - microbiology
Gram-Negative Bacterial Infections - epidemiology
Gram-Negative Bacterial Infections - microbiology
Humans
Infant
Infectious Disease
Middle Aged
Phylogeny
Sequence Analysis, DNA
Virulence
Virulence Factors - genetics
Virulence-associated genes
Water Microbiology
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Summary Objectives To determine the prevalence of Aeromonas infections in diarrheal patients, the distribution of virulence-associated genes and antibiotic resistance among different Aeromonas species in China. Methods We conducted continual active surveillance aimed on Aeromonas from diarrheal patients and aquatic samples. Aeromonas strains were identified by biochemical tests, further confirmed to species level by a multilocus phylogenetic analysis. Potential virulence genes were detected by PCR. Antibiotics susceptibility testing was carried based on the minimal inhibitory concentration. Results From 5069 samples (stool specimens, n  = 4529; water samples, n  = 540) in China, 257 Aeromonas isolates [stools, n  = 193 (4.3%); water, n  = 64 (11.9%)] were identified by biochemical tests. The most common species from stools and water were Aeromonas veronii (42.5%) and Aeromonas caviae (37.5%), respectively. Distribution of five potential genes were significantly different between stool and water samples, two genes ( ast and alt ) were higher in stool than in water samples ( P  
ISSN:0163-4453
1532-2742
DOI:10.1016/j.jinf.2014.11.004