Delivering nanomedicines to patients: A practical guide

Abstract This is a perspective on the current state of development of nanomedicines in Europe. The view is expressed that a much higher translational success rate could be achieved, with rewards for all stakeholders, if researchers understood the industrial decision points required for new drugs. Ge...

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Bibliographic Details
Published in:Nanomedicine 2015-05, Vol.11 (4), p.983-992
Main Authors: Eaton, Mike A.W., PhD, Levy, Laurent, PhD, Fontaine, Olivier M.A., MSc
Format: Article
Language:English
Subjects:
Commercialize
Delivery of Health Care - methods
Delivery of Health Care - trends
Development
Europe
Humans
Internal Medicine
Milestones
Nanomedicine - methods
Nanomedicine - trends
Translation
TRL
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Summary:Abstract This is a perspective on the current state of development of nanomedicines in Europe. The view is expressed that a much higher translational success rate could be achieved, with rewards for all stakeholders, if researchers understood the industrial decision points required for new drugs. Getting a drug through the clinic will not help patients unless it is developable by industry. This article is written in the hope that it will help researchers and SMEs to decide where they are in the established process, whether they are making progress and to determine what to do next. It attempts to map the early stages from ideation to first (time) in man (FIM). From the Clinical Editor The field of nanomedicine has come a long way in the past decade. The overall dream of any researcher in this field remains the realization of concept to clinical product. In this paper, the authors outlined for the readers, the underlying problems and actions that need to be done, so that current challenges can be solved.
ISSN:1549-9634
1549-9642
DOI:10.1016/j.nano.2015.02.004