Inside Cover: Novel 1,4-Substituted-1,2,3-Triazoles as Antitubercular Agents (ChemMedChem 5/2015)

The inside cover picture shows that 30% of the world population is infected with TB. In 2013, it caused 1.5million deaths, and the incidence of drug resistance is increasing. TB's prevalence in low- and medium-income countries means that new therapies must be accessed quickly and cheaply. Simpl...

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Bibliographic Details
Published in:ChemMedChem 2015-05, Vol.10 (5), p.758-758
Main Authors: Altimari, Jarrad M., Hockey, Samantha C., Boshoff, Helena I., Sajid, Andaleeb, Henderson, Luke C.
Format: Article
Language:English
Subjects:
antibacterial agents
azides
click chemistry
Mycobacterium tuberculosis
triazoles
tuberculosis
Online Access:Get full text
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Summary:The inside cover picture shows that 30% of the world population is infected with TB. In 2013, it caused 1.5million deaths, and the incidence of drug resistance is increasing. TB's prevalence in low- and medium-income countries means that new therapies must be accessed quickly and cheaply. Simple 1,2,3-triazoles were assembled via click chemistry in high crude purity and in moderate to high yield, and serve as excellent starting points for development of potent therapies. For further details, see the Communication by LukeC. Henderson et al. on
ISSN:1860-7179
1860-7187
DOI:10.1002/cmdc.201590012