Posterior choroidal leiomyoma: a rare case report and literature review

We report a literature review and detailed evaluation of a rare case of posterior choroidal leiomyoma to emphasize the importance of differentiating this from other choroidal tumors. A 30‐year‐old male presented with variable blurred vision in his right eye secondary to a choroidal tumor. Clinical e...

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Bibliographic Details
Published in:APMIS : acta pathologica, microbiologica et immunologica Scandinavica microbiologica et immunologica Scandinavica, 2015-06, Vol.123 (6), p.540-545
Main Authors: Chiang, Wei‐Yu, Lin, Jui‐Wei, Yang, I‐Hui, Kuo, Hsi‐Kung
Format: Article
Language:English
Subjects:
Adult
Choroid Neoplasms - diagnosis
Choroid Neoplasms - pathology
Choroid Neoplasms - therapy
Choroidal leiomyoma
choroidal tumor
Fibroids
Humans
Leiomyoma - diagnosis
Leiomyoma - pathology
Leiomyoma - therapy
Literature reviews
Male
Melanoma - diagnosis
Melanoma - pathology
Melanoma - therapy
Skin cancer
smooth muscle tumor
Tomography
Uveal Neoplasms - diagnosis
Uveal Neoplasms - pathology
Uveal Neoplasms - therapy
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Summary:We report a literature review and detailed evaluation of a rare case of posterior choroidal leiomyoma to emphasize the importance of differentiating this from other choroidal tumors. A 30‐year‐old male presented with variable blurred vision in his right eye secondary to a choroidal tumor. Clinical examinations were performed including fundus photography, optical coherence tomography, B scans, fluorescein and indocyanine green angiography, computed tomography, and magnetic resonance imaging. Preoperative examination revealed a suspected choroidal melanoma and enucleation was performed. However, a definitive diagnosis of choroidal leiomyoma was made following postoperative pathological light microscopy and immunohistochemical studies. Published case reports were collected and the common characteristics and distinctive features were compared with the current case. Posterior choroidal leiomyoma was summarized from the literature, and beneficial information for diagnosis and treatment was obtained. In conclusion, posterior choroidal leiomyoma is rare and should be differentiated from amelanotic melanomas. Despite the benign nature, an explanation regarding the rare incidence and difficult diagnosis of posterior choroidal leiomyoma must be provided to patients, prior to enucleation or detrimental treatment.
ISSN:0903-4641
1600-0463
DOI:10.1111/apm.12384