Posterior choroidal leiomyoma: a rare case report and literature review

• Published in: APMIS : acta pathologica, microbiologica et immunologica Scandinavica microbiologica et immunologica Scandinavica, 2015-06, Vol.123 (6), p.540-545
• Main Authors: Chiang, Wei‐Yu, Lin, Jui‐Wei, Yang, I‐Hui, Kuo, Hsi‐Kung
• Format: Article
• Language: English
• Subjects: Adult; Choroid Neoplasms - diagnosis; Choroid Neoplasms - pathology; Choroid Neoplasms - therapy; Choroidal leiomyoma; choroidal tumor; Fibroids; Humans; Leiomyoma - diagnosis; Leiomyoma - pathology; Leiomyoma - therapy; Literature reviews; Male; Melanoma - diagnosis; Melanoma - pathology; Melanoma - therapy; Skin cancer; smooth muscle tumor; Tomography; Uveal Neoplasms - diagnosis; Uveal Neoplasms - pathology; Uveal Neoplasms - therapy
• ISSN: 0903-4641; 1600-0463
• DOI: 10.1111/apm.12384

We report a literature review and detailed evaluation of a rare case of posterior choroidal leiomyoma to emphasize the importance of differentiating this from other choroidal tumors. A 30‐year‐old male presented with variable blurred vision in his right eye secondary to a choroidal tumor. Clinical examinations were performed including fundus photography, optical coherence tomography, B scans, fluorescein and indocyanine green angiography, computed tomography, and magnetic resonance imaging. Preoperative examination revealed a suspected choroidal melanoma and enucleation was performed. However, a definitive diagnosis of choroidal leiomyoma was made following postoperative pathological light microscopy and immunohistochemical studies. Published case reports were collected and the common characteristics and distinctive features were compared with the current case. Posterior choroidal leiomyoma was summarized from the literature, and beneficial information for diagnosis and treatment was obtained. In conclusion, posterior choroidal leiomyoma is rare and should be differentiated from amelanotic melanomas. Despite the benign nature, an explanation regarding the rare incidence and difficult diagnosis of posterior choroidal leiomyoma must be provided to patients, prior to enucleation or detrimental treatment.