Clinical use of conditioned media of adipose tissue-derived stem cells in female pattern hair loss: a retrospective case series study

Background Female pattern hair loss (FPHL) is a common disorder but presents severe psychosocial problems in many female patients. Adipose tissue‐derived stem cells (ADSCs) and conditioned media of ADSCs (ADSC‐CM) are reported to promote hair growth in vitro. However, there are no clinical reports o...

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Bibliographic Details
Published in:International journal of dermatology 2015-06, Vol.54 (6), p.730-735
Main Authors: Shin, Hyoseung, Ryu, Hyeong Ho, Kwon, Ohsang, Park, Byung-Soon, Jo, Seong Jin
Format: Article
Language:English
Subjects:
Adipose Tissue - cytology
Adult
Aged
Alopecia - surgery
Culture Media, Conditioned
Female
Humans
Middle Aged
Retrospective Studies
Stem Cell Transplantation
Young Adult
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Summary:Background Female pattern hair loss (FPHL) is a common disorder but presents severe psychosocial problems in many female patients. Adipose tissue‐derived stem cells (ADSCs) and conditioned media of ADSCs (ADSC‐CM) are reported to promote hair growth in vitro. However, there are no clinical reports on the treatment of alopecia using ADSC‐CM. Objectives This study evaluates our clinical experience in the use of ADSC‐CM for the treatment of FPHL. Methods A retrospective, observational study of outcomes in 27 patients with FPHL treated with ADSC‐CM was performed. To evaluate the efficacy of the treatment, patients’ medical records and phototrichographic images were analyzed. Results The application of ADSC‐CM showed efficacy in treating FPHL after 12 weeks of therapy. Hair density increased from 105.4 to 122.7 hairs/cm2 (P 
ISSN:0011-9059
1365-4632
DOI:10.1111/ijd.12650