Loading…
Clinical use of conditioned media of adipose tissue-derived stem cells in female pattern hair loss: a retrospective case series study
Background Female pattern hair loss (FPHL) is a common disorder but presents severe psychosocial problems in many female patients. Adipose tissue‐derived stem cells (ADSCs) and conditioned media of ADSCs (ADSC‐CM) are reported to promote hair growth in vitro. However, there are no clinical reports o...
Saved in:
| Published in: | International journal of dermatology 2015-06, Vol.54 (6), p.730-735 |
|---|---|
| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c4990-c60460a4cfa299d5f663071524a548073fce21288f054865969c0f83c50840a23 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c4990-c60460a4cfa299d5f663071524a548073fce21288f054865969c0f83c50840a23 |
| container_end_page | 735 |
| container_issue | 6 |
| container_start_page | 730 |
| container_title | International journal of dermatology |
| container_volume | 54 |
| creator | Shin, Hyoseung Ryu, Hyeong Ho Kwon, Ohsang Park, Byung-Soon Jo, Seong Jin |
| description | Background
Female pattern hair loss (FPHL) is a common disorder but presents severe psychosocial problems in many female patients. Adipose tissue‐derived stem cells (ADSCs) and conditioned media of ADSCs (ADSC‐CM) are reported to promote hair growth in vitro. However, there are no clinical reports on the treatment of alopecia using ADSC‐CM.
Objectives
This study evaluates our clinical experience in the use of ADSC‐CM for the treatment of FPHL.
Methods
A retrospective, observational study of outcomes in 27 patients with FPHL treated with ADSC‐CM was performed. To evaluate the efficacy of the treatment, patients’ medical records and phototrichographic images were analyzed.
Results
The application of ADSC‐CM showed efficacy in treating FPHL after 12 weeks of therapy. Hair density increased from 105.4 to 122.7 hairs/cm2 (P |
| doi_str_mv | 10.1111/ijd.12650 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1683756310</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1683756310</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4990-c60460a4cfa299d5f663071524a548073fce21288f054865969c0f83c50840a23</originalsourceid><addsrcrecordid>eNp1kE1PFTEUhhuCkQu68A-YLmEx0O9O3ckFAQMaEw3LpnROQ2G-aGfU-wP83_ZygR3dNKfnPU9OH4Q-UHJIyzmKd80hZUqSLbSgXMlKKM620YIQSitDpNlBuznflZIzKt6iHSa11kaTBfq3bGMfvWvxnAEPAfuhb-IUhx4a3EET3frRNXEcSn-KOc9QNZDi79LPE3TYQ9tmHHscoHMt4NFNE6Qe37qYcDvk_Ak7nGBKQx7BT2UQe1dYuUAgF8bcrN6hN8G1Gd4_3Xvo15fTn8vz6vL72cXy82XlhTGk8ooIRZzwwTFjGhmU4kRTyYSToiaaBw-MsroOpNRKGmU8CTX3ktSCOMb30P6GO6bhYYY82S7m9QdcD8OcLVU111JxSkr0YBP1ZfGcINgxxc6llaXErq3bYt0-Wi_Zj0_Y-aY4e0k-ay6Bo03gT2xh9TrJXnw9eUZWm4lYJP99mXDp3ipddrTX386suaqvj8XxD6v5f9epmv0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1683756310</pqid></control><display><type>article</type><title>Clinical use of conditioned media of adipose tissue-derived stem cells in female pattern hair loss: a retrospective case series study</title><source>Wiley</source><creator>Shin, Hyoseung ; Ryu, Hyeong Ho ; Kwon, Ohsang ; Park, Byung-Soon ; Jo, Seong Jin</creator><creatorcontrib>Shin, Hyoseung ; Ryu, Hyeong Ho ; Kwon, Ohsang ; Park, Byung-Soon ; Jo, Seong Jin</creatorcontrib><description>Background
Female pattern hair loss (FPHL) is a common disorder but presents severe psychosocial problems in many female patients. Adipose tissue‐derived stem cells (ADSCs) and conditioned media of ADSCs (ADSC‐CM) are reported to promote hair growth in vitro. However, there are no clinical reports on the treatment of alopecia using ADSC‐CM.
Objectives
This study evaluates our clinical experience in the use of ADSC‐CM for the treatment of FPHL.
Methods
A retrospective, observational study of outcomes in 27 patients with FPHL treated with ADSC‐CM was performed. To evaluate the efficacy of the treatment, patients’ medical records and phototrichographic images were analyzed.
Results
The application of ADSC‐CM showed efficacy in treating FPHL after 12 weeks of therapy. Hair density increased from 105.4 to 122.7 hairs/cm2 (P < 0.001). Hair thickness increased from 57.5 μm to 64.0 μm (P < 0.001). None of the patients reported severe adverse reactions.
Conclusions
The application of ADSC‐CM is a potential treatment option for FPHL.</description><identifier>ISSN: 0011-9059</identifier><identifier>EISSN: 1365-4632</identifier><identifier>DOI: 10.1111/ijd.12650</identifier><identifier>PMID: 25777970</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Adipose Tissue - cytology ; Adult ; Aged ; Alopecia - surgery ; Culture Media, Conditioned ; Female ; Humans ; Middle Aged ; Retrospective Studies ; Stem Cell Transplantation ; Young Adult</subject><ispartof>International journal of dermatology, 2015-06, Vol.54 (6), p.730-735</ispartof><rights>2015 The International Society of Dermatology</rights><rights>2015 The International Society of Dermatology.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4990-c60460a4cfa299d5f663071524a548073fce21288f054865969c0f83c50840a23</citedby><cites>FETCH-LOGICAL-c4990-c60460a4cfa299d5f663071524a548073fce21288f054865969c0f83c50840a23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25777970$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shin, Hyoseung</creatorcontrib><creatorcontrib>Ryu, Hyeong Ho</creatorcontrib><creatorcontrib>Kwon, Ohsang</creatorcontrib><creatorcontrib>Park, Byung-Soon</creatorcontrib><creatorcontrib>Jo, Seong Jin</creatorcontrib><title>Clinical use of conditioned media of adipose tissue-derived stem cells in female pattern hair loss: a retrospective case series study</title><title>International journal of dermatology</title><addtitle>Int J Dermatol</addtitle><description>Background
Female pattern hair loss (FPHL) is a common disorder but presents severe psychosocial problems in many female patients. Adipose tissue‐derived stem cells (ADSCs) and conditioned media of ADSCs (ADSC‐CM) are reported to promote hair growth in vitro. However, there are no clinical reports on the treatment of alopecia using ADSC‐CM.
Objectives
This study evaluates our clinical experience in the use of ADSC‐CM for the treatment of FPHL.
Methods
A retrospective, observational study of outcomes in 27 patients with FPHL treated with ADSC‐CM was performed. To evaluate the efficacy of the treatment, patients’ medical records and phototrichographic images were analyzed.
Results
The application of ADSC‐CM showed efficacy in treating FPHL after 12 weeks of therapy. Hair density increased from 105.4 to 122.7 hairs/cm2 (P < 0.001). Hair thickness increased from 57.5 μm to 64.0 μm (P < 0.001). None of the patients reported severe adverse reactions.
Conclusions
The application of ADSC‐CM is a potential treatment option for FPHL.</description><subject>Adipose Tissue - cytology</subject><subject>Adult</subject><subject>Aged</subject><subject>Alopecia - surgery</subject><subject>Culture Media, Conditioned</subject><subject>Female</subject><subject>Humans</subject><subject>Middle Aged</subject><subject>Retrospective Studies</subject><subject>Stem Cell Transplantation</subject><subject>Young Adult</subject><issn>0011-9059</issn><issn>1365-4632</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNp1kE1PFTEUhhuCkQu68A-YLmEx0O9O3ckFAQMaEw3LpnROQ2G-aGfU-wP83_ZygR3dNKfnPU9OH4Q-UHJIyzmKd80hZUqSLbSgXMlKKM620YIQSitDpNlBuznflZIzKt6iHSa11kaTBfq3bGMfvWvxnAEPAfuhb-IUhx4a3EET3frRNXEcSn-KOc9QNZDi79LPE3TYQ9tmHHscoHMt4NFNE6Qe37qYcDvk_Ak7nGBKQx7BT2UQe1dYuUAgF8bcrN6hN8G1Gd4_3Xvo15fTn8vz6vL72cXy82XlhTGk8ooIRZzwwTFjGhmU4kRTyYSToiaaBw-MsroOpNRKGmU8CTX3ktSCOMb30P6GO6bhYYY82S7m9QdcD8OcLVU111JxSkr0YBP1ZfGcINgxxc6llaXErq3bYt0-Wi_Zj0_Y-aY4e0k-ay6Bo03gT2xh9TrJXnw9eUZWm4lYJP99mXDp3ipddrTX386suaqvj8XxD6v5f9epmv0</recordid><startdate>201506</startdate><enddate>201506</enddate><creator>Shin, Hyoseung</creator><creator>Ryu, Hyeong Ho</creator><creator>Kwon, Ohsang</creator><creator>Park, Byung-Soon</creator><creator>Jo, Seong Jin</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201506</creationdate><title>Clinical use of conditioned media of adipose tissue-derived stem cells in female pattern hair loss: a retrospective case series study</title><author>Shin, Hyoseung ; Ryu, Hyeong Ho ; Kwon, Ohsang ; Park, Byung-Soon ; Jo, Seong Jin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4990-c60460a4cfa299d5f663071524a548073fce21288f054865969c0f83c50840a23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Adipose Tissue - cytology</topic><topic>Adult</topic><topic>Aged</topic><topic>Alopecia - surgery</topic><topic>Culture Media, Conditioned</topic><topic>Female</topic><topic>Humans</topic><topic>Middle Aged</topic><topic>Retrospective Studies</topic><topic>Stem Cell Transplantation</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shin, Hyoseung</creatorcontrib><creatorcontrib>Ryu, Hyeong Ho</creatorcontrib><creatorcontrib>Kwon, Ohsang</creatorcontrib><creatorcontrib>Park, Byung-Soon</creatorcontrib><creatorcontrib>Jo, Seong Jin</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shin, Hyoseung</au><au>Ryu, Hyeong Ho</au><au>Kwon, Ohsang</au><au>Park, Byung-Soon</au><au>Jo, Seong Jin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical use of conditioned media of adipose tissue-derived stem cells in female pattern hair loss: a retrospective case series study</atitle><jtitle>International journal of dermatology</jtitle><addtitle>Int J Dermatol</addtitle><date>2015-06</date><risdate>2015</risdate><volume>54</volume><issue>6</issue><spage>730</spage><epage>735</epage><pages>730-735</pages><issn>0011-9059</issn><eissn>1365-4632</eissn><abstract>Background
Female pattern hair loss (FPHL) is a common disorder but presents severe psychosocial problems in many female patients. Adipose tissue‐derived stem cells (ADSCs) and conditioned media of ADSCs (ADSC‐CM) are reported to promote hair growth in vitro. However, there are no clinical reports on the treatment of alopecia using ADSC‐CM.
Objectives
This study evaluates our clinical experience in the use of ADSC‐CM for the treatment of FPHL.
Methods
A retrospective, observational study of outcomes in 27 patients with FPHL treated with ADSC‐CM was performed. To evaluate the efficacy of the treatment, patients’ medical records and phototrichographic images were analyzed.
Results
The application of ADSC‐CM showed efficacy in treating FPHL after 12 weeks of therapy. Hair density increased from 105.4 to 122.7 hairs/cm2 (P < 0.001). Hair thickness increased from 57.5 μm to 64.0 μm (P < 0.001). None of the patients reported severe adverse reactions.
Conclusions
The application of ADSC‐CM is a potential treatment option for FPHL.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>25777970</pmid><doi>10.1111/ijd.12650</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0011-9059 |
| ispartof | International journal of dermatology, 2015-06, Vol.54 (6), p.730-735 |
| issn | 0011-9059 1365-4632 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1683756310 |
| source | Wiley |
| subjects | Adipose Tissue - cytology Adult Aged Alopecia - surgery Culture Media, Conditioned Female Humans Middle Aged Retrospective Studies Stem Cell Transplantation Young Adult |
| title | Clinical use of conditioned media of adipose tissue-derived stem cells in female pattern hair loss: a retrospective case series study |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T04%3A39%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Clinical%20use%20of%20conditioned%20media%20of%20adipose%20tissue-derived%20stem%20cells%20in%20female%20pattern%20hair%20loss:%20a%20retrospective%20case%20series%20study&rft.jtitle=International%20journal%20of%20dermatology&rft.au=Shin,%20Hyoseung&rft.date=2015-06&rft.volume=54&rft.issue=6&rft.spage=730&rft.epage=735&rft.pages=730-735&rft.issn=0011-9059&rft.eissn=1365-4632&rft_id=info:doi/10.1111/ijd.12650&rft_dat=%3Cproquest_cross%3E1683756310%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c4990-c60460a4cfa299d5f663071524a548073fce21288f054865969c0f83c50840a23%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1683756310&rft_id=info:pmid/25777970&rfr_iscdi=true |