Clinical performance of serum isoform [‐2]proPSA (p2PSA), and its derivatives %p2PSA and the Prostate Health Index, in men aged <60 years: results from a multicentric European study

Objectives To test the hypothesis that [‐2]proPSA (p2PSA) and its derivatives are more accurate than total prostate‐specific antigen (tPSA), free prostate‐specific antigen (fPSA) and fPSA as percentage of tPSA (%fPSA) in detecting prostate cancer (PCa) in men aged

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Bibliographic Details
Published in:BJU international 2015-06, Vol.115 (6), p.913-920
Main Authors: Fossati, Nicola, Lazzeri, Massimo, Haese, Alexander, McNicholas, Thomas, Taille, Alexandre, Buffi, Nicolò Maria, Lughezzani, Giovanni, Gadda, Giulio Maria, Lista, Giuliana, Larcher, Alessandro, Abrate, Alberto, Mistretta, Francesco, Bini, Vittorio, Redorta, Joan Palou, Graefen, Markus, Guazzoni, Giorgio
Format: Article
Language:English
Subjects:
Accuracy
Age Factors
Antigens
Case-Control Studies
Health Status Indicators
Humans
Male
Mens health
Middle Aged
Models, Statistical
p2PSA
predictive models
Predictive Value of Tests
prostate biopsy
Prostate cancer
prostate health index
Prostate-Specific Antigen - blood
Prostatic Neoplasms - blood
Prostatic Neoplasms - diagnosis
Prostatic Neoplasms - epidemiology
Protein Isoforms
PSA
ROC Curve
young men
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Summary:Objectives To test the hypothesis that [‐2]proPSA (p2PSA) and its derivatives are more accurate than total prostate‐specific antigen (tPSA), free prostate‐specific antigen (fPSA) and fPSA as percentage of tPSA (%fPSA) in detecting prostate cancer (PCa) in men aged
ISSN:1464-4096
1464-410X
DOI:10.1111/bju.12718