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Insulinoma in a patient with type 2 diabetes mellitus
Insulinoma in a patient with pre-existing diabetes is extremely rare. Only a small number of cases have been reported all over the world. We report a case of insulinoma in a patient with type 2 diabetes. A 63-year-old female was diagnosed to have diabetes mellitus six years ago, she was given metfor...
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Published in: | Acta medica Iranica 2015, Vol.53 (5), p.317-319 |
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container_title | Acta medica Iranica |
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creator | Ghafoori, Shahnaz Lankarani, Mahnaz |
description | Insulinoma in a patient with pre-existing diabetes is extremely rare. Only a small number of cases have been reported all over the world. We report a case of insulinoma in a patient with type 2 diabetes. A 63-year-old female was diagnosed to have diabetes mellitus six years ago, she was given metformin and sulphonylurea to control her glycemia, she had adequate glycemic control for many years, but thereafter, the patient has experienced hypoglycemia after cessation of the treatment since 8 months ago and was hospitalized for further examination, endogenous hypoglycemia was confirmed and the level of serum insulin and C-peptide were elevated. Endoscopic ultrasound showed a heterogeneous lesion in the head of the pancreas. Head pancreatectomy was done. In the postoperative period diabetes again developed and required oral agents for control. |
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Only a small number of cases have been reported all over the world. We report a case of insulinoma in a patient with type 2 diabetes. A 63-year-old female was diagnosed to have diabetes mellitus six years ago, she was given metformin and sulphonylurea to control her glycemia, she had adequate glycemic control for many years, but thereafter, the patient has experienced hypoglycemia after cessation of the treatment since 8 months ago and was hospitalized for further examination, endogenous hypoglycemia was confirmed and the level of serum insulin and C-peptide were elevated. Endoscopic ultrasound showed a heterogeneous lesion in the head of the pancreas. Head pancreatectomy was done. In the postoperative period diabetes again developed and required oral agents for control.</description><identifier>EISSN: 1735-9694</identifier><identifier>PMID: 26024708</identifier><language>eng</language><publisher>Iran</publisher><subject>Blood Glucose ; Diabetes Mellitus, Type 2 - drug therapy ; Diabetes Mellitus, Type 2 - physiopathology ; Endosonography ; Female ; Humans ; Hypoglycemia - diagnosis ; Hypoglycemia - etiology ; Insulinoma - diagnosis ; Insulinoma - pathology ; Middle Aged ; Pancreatic Neoplasms - diagnosis ; Pancreatic Neoplasms - pathology ; Postoperative Period</subject><ispartof>Acta medica Iranica, 2015, Vol.53 (5), p.317-319</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4022,37012</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26024708$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ghafoori, Shahnaz</creatorcontrib><creatorcontrib>Lankarani, Mahnaz</creatorcontrib><title>Insulinoma in a patient with type 2 diabetes mellitus</title><title>Acta medica Iranica</title><addtitle>Acta Med Iran</addtitle><description>Insulinoma in a patient with pre-existing diabetes is extremely rare. Only a small number of cases have been reported all over the world. We report a case of insulinoma in a patient with type 2 diabetes. A 63-year-old female was diagnosed to have diabetes mellitus six years ago, she was given metformin and sulphonylurea to control her glycemia, she had adequate glycemic control for many years, but thereafter, the patient has experienced hypoglycemia after cessation of the treatment since 8 months ago and was hospitalized for further examination, endogenous hypoglycemia was confirmed and the level of serum insulin and C-peptide were elevated. Endoscopic ultrasound showed a heterogeneous lesion in the head of the pancreas. Head pancreatectomy was done. In the postoperative period diabetes again developed and required oral agents for control.</description><subject>Blood Glucose</subject><subject>Diabetes Mellitus, Type 2 - drug therapy</subject><subject>Diabetes Mellitus, Type 2 - physiopathology</subject><subject>Endosonography</subject><subject>Female</subject><subject>Humans</subject><subject>Hypoglycemia - diagnosis</subject><subject>Hypoglycemia - etiology</subject><subject>Insulinoma - diagnosis</subject><subject>Insulinoma - pathology</subject><subject>Middle Aged</subject><subject>Pancreatic Neoplasms - diagnosis</subject><subject>Pancreatic Neoplasms - pathology</subject><subject>Postoperative Period</subject><issn>1735-9694</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNo1j0tLAzEURoMgttb-BcnSzUCSe5NMllJ8FArd6HrITO7QyLycZJD-ewvW1dkcDt93w9bSgi6ccbhi9yl9CQGlkvaOrZQRCq0o10zvh7R0cRh7z-PAPZ98jjRk_hPziefzRFzxEH1NmRLvqetiXtIDu219l2h75YZ9vr587N6Lw_Ftv3s-FJN0JheNDE1jsUUBwoGztZdO2ZpEUKVQWjsIRtgyoKFWgDQmKIVoNdoaAiqCDXv6607z-L1QylUfU3MZ4Qcal1RJUyICGg0X9fGqLnVPoZrm2Pv5XP1fhV9nXExt</recordid><startdate>2015</startdate><enddate>2015</enddate><creator>Ghafoori, Shahnaz</creator><creator>Lankarani, Mahnaz</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>2015</creationdate><title>Insulinoma in a patient with type 2 diabetes mellitus</title><author>Ghafoori, Shahnaz ; Lankarani, Mahnaz</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p196t-c1dcc74f40309397ba1927be0d28025593d6078d46ef03166d22447547b3d42e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Blood Glucose</topic><topic>Diabetes Mellitus, Type 2 - drug therapy</topic><topic>Diabetes Mellitus, Type 2 - physiopathology</topic><topic>Endosonography</topic><topic>Female</topic><topic>Humans</topic><topic>Hypoglycemia - diagnosis</topic><topic>Hypoglycemia - etiology</topic><topic>Insulinoma - diagnosis</topic><topic>Insulinoma - pathology</topic><topic>Middle Aged</topic><topic>Pancreatic Neoplasms - diagnosis</topic><topic>Pancreatic Neoplasms - pathology</topic><topic>Postoperative Period</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ghafoori, Shahnaz</creatorcontrib><creatorcontrib>Lankarani, Mahnaz</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Acta medica Iranica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ghafoori, Shahnaz</au><au>Lankarani, Mahnaz</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Insulinoma in a patient with type 2 diabetes mellitus</atitle><jtitle>Acta medica Iranica</jtitle><addtitle>Acta Med Iran</addtitle><date>2015</date><risdate>2015</risdate><volume>53</volume><issue>5</issue><spage>317</spage><epage>319</epage><pages>317-319</pages><eissn>1735-9694</eissn><abstract>Insulinoma in a patient with pre-existing diabetes is extremely rare. Only a small number of cases have been reported all over the world. We report a case of insulinoma in a patient with type 2 diabetes. A 63-year-old female was diagnosed to have diabetes mellitus six years ago, she was given metformin and sulphonylurea to control her glycemia, she had adequate glycemic control for many years, but thereafter, the patient has experienced hypoglycemia after cessation of the treatment since 8 months ago and was hospitalized for further examination, endogenous hypoglycemia was confirmed and the level of serum insulin and C-peptide were elevated. Endoscopic ultrasound showed a heterogeneous lesion in the head of the pancreas. Head pancreatectomy was done. In the postoperative period diabetes again developed and required oral agents for control.</abstract><cop>Iran</cop><pmid>26024708</pmid><tpages>3</tpages></addata></record> |
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identifier | EISSN: 1735-9694 |
ispartof | Acta medica Iranica, 2015, Vol.53 (5), p.317-319 |
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language | eng |
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source | Publicly Available Content (ProQuest) |
subjects | Blood Glucose Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - physiopathology Endosonography Female Humans Hypoglycemia - diagnosis Hypoglycemia - etiology Insulinoma - diagnosis Insulinoma - pathology Middle Aged Pancreatic Neoplasms - diagnosis Pancreatic Neoplasms - pathology Postoperative Period |
title | Insulinoma in a patient with type 2 diabetes mellitus |
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