PVP Assisted Synthesis of Hydroxyapatite Nanorods with Tunable Aspect Ratio and Bioactivity

Highly crystalline and reasonably uniform hydroxyapatite (HA) nanorods were prepared by polyvinylpyrrolidone (PVP) assisted hydrothermal synthesis which produces high aspect ratio (length/width) nanorods. The aspect ratio of the nanorods was higher in the presence of PVP and increased with increasin...

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Bibliographic Details
Published in:Journal of nanomaterials 2015-01, Vol.2015 (2015), p.1-9
Main Authors: Nathanael, A. Joseph, Oh, Tae Hwan, Seo, Young Ho
Format: Article
Language:English
Subjects:
Aspect ratio
Biocompatibility
Biological activity
Cell growth
Field emission
H alpha line
High aspect ratio
Hydroxyapatite
Morphology
Nanomaterials
Nanorods
Particle size
Surface chemistry
Synthesis
Tuning
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Summary:Highly crystalline and reasonably uniform hydroxyapatite (HA) nanorods were prepared by polyvinylpyrrolidone (PVP) assisted hydrothermal synthesis which produces high aspect ratio (length/width) nanorods. The aspect ratio of the nanorods was higher in the presence of PVP and increased with increasing concentrations of PVP. X-ray diffraction (XRD) analysis showed that the HA nanorods were of the hexagonal apatite phase. High resolution transmission electron microscopy (HRTEM) and selected area electron diffraction (SAED) patterns confirmed that the nanorods grew in the c-axis direction (preferred orientation). The calculated lattice spacing was ~0.35 nm which is the c-axis value of hexagonal HA. Morphological variations of pristine and PVP added HA were evaluated by field emission scanning electron microscopy (FESEM) and TEM, which revealed that the presence of PVP greatly increased the aspect ratio of the HA nanorods. The formation mechanism of the PVP assisted HA was studied and a possible reaction model was given. Cell viability analysis by in vitro studies showed encouraging results for the high aspect ratio nanorods and indicated a possibility for tuning the activity based on controlling the aspect ratio.
ISSN:1687-4110
1687-4129
DOI:10.1155/2015/621785