K-t GRAPPA-accelerated 4D flow MRI of liver hemodynamics: influence of different acceleration factors on qualitative and quantitative assessment of blood flow

Objective We sought to evaluate the feasibility of k-t parallel imaging for accelerated 4D flow MRI in the hepatic vascular system by investigating the impact of different acceleration factors. Materials and methods k-t GRAPPA accelerated 4D flow MRI of the liver vasculature was evaluated in 16 heal...

Full description

Saved in:
Bibliographic Details
Published in:Magma (New York, N.Y.) N.Y.), 2015-04, Vol.28 (2), p.149-159
Main Authors: Stankovic, Zoran, Fink, Jury, Collins, Jeremy D., Semaan, Edouard, Russe, Maximilian F., Carr, James C., Markl, Michael, Langer, Mathias, Jung, Bernd
Format: Article
Language:English
Subjects:
Acceleration
Adult
Assessments
Biomedical Engineering and Bioengineering
Blood Flow Velocity - physiology
Computer Appl. in Life Sciences
Feasibility Studies
Female
Health Informatics
Hemodynamics
Humans
Image Enhancement - methods
Image Interpretation, Computer-Assisted - methods
Imaging
Imaging, Three-Dimensional - methods
Liver
Liver - anatomy & histology
Liver - physiology
Liver Circulation - physiology
Magnetic resonance
Magnetic Resonance Angiography - methods
Magnetic resonance imaging
Medicine & Public Health
Radiology
Reproducibility of Results
Research Article
Respiratory-Gated Imaging Techniques - methods
Sensitivity and Specificity
Shear Strength - physiology
Solid State Physics
Three dimensional
Veins
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective We sought to evaluate the feasibility of k-t parallel imaging for accelerated 4D flow MRI in the hepatic vascular system by investigating the impact of different acceleration factors. Materials and methods k-t GRAPPA accelerated 4D flow MRI of the liver vasculature was evaluated in 16 healthy volunteers at 3T with acceleration factors R  = 3, R  = 5, and R  = 8 (2.0 × 2.5 × 2.4 mm 3 , TR = 82 ms), and R  = 5 (TR = 41 ms); GRAPPA R  = 2 was used as the reference standard. Qualitative flow analysis included grading of 3D streamlines and time-resolved particle traces. Quantitative evaluation assessed velocities, net flow, and wall shear stress (WSS). Results Significant scan time savings were realized for all acceleration factors compared to standard GRAPPA R  = 2 (21–71 %) ( p  
ISSN:0968-5243
1352-8661
DOI:10.1007/s10334-014-0456-1