Red blood cell distribution width is increased in patients with psoriasis vulgaris: A retrospective study on 261 patients

Circulating inflammatory cytokines and markers are increased in patients with psoriasis. Recent studies have shown that a higher red blood cell distribution width (RDW) is associated with disease activity in various disorders. Our objective was to investigate whether RDW is increased in psoriasis pa...

Full description

Saved in:
Bibliographic Details
Published in:Journal of dermatology 2015-06, Vol.42 (6), p.567-571
Main Authors: Kim, Das Suk, Shin, Dongyun, Jee, Hyunjoong, Kim, Tae-Gyun, Kim, Sung Hee, Kim, Do Young, Kim, Soo Min, Lee, Min-Geol
Format: Article
Language:English
Subjects:
Adult
C-reactive protein
Case-Control Studies
Erythrocyte Indices
erythrocyte sedimentation rate
Female
Humans
inflammation
Male
Middle Aged
Pharmaceutical industry
Psoriasis
Psoriasis - blood
Psoriasis Area Severity Index
psoriasis vulgaris
red blood cell distribution width
Retrospective Studies
Severity of Illness Index
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Circulating inflammatory cytokines and markers are increased in patients with psoriasis. Recent studies have shown that a higher red blood cell distribution width (RDW) is associated with disease activity in various disorders. Our objective was to investigate whether RDW is increased in psoriasis patients, and to evaluate its possible association with disease severity. We conducted a retrospective study of psoriasis patients seen in a university hospital in South Korea. Information about demographics, hematological parameters and disease severity were collected. Statistical analysis was performed using Student's t‐test, multivariable logistic regression, Fisher's exact test and Spearman's rank correlation coefficient analysis as appropriate. A total of 261 psoriasis patients and 102 healthy controls were included in our study. The mean RDW value was significantly increased in psoriasis patients compared with healthy control (P = 0.037). Compared with mild psoriasis patients (Psoriasis Area and Severity Index [PASI],
ISSN:0385-2407
1346-8138
DOI:10.1111/1346-8138.12865