Somatostatin Receptors in an Anaplastic Oligodendroglioma Relapse Evidenced By 68Ga DOTANOC PET/CT

ABSTRACTSix years ago, a right frontal lobe anaplastic oligodendroglioma negative for AE1/AE3 and HBM-45, positive for 1p/19q deletion, EMA, GFAP, and synaptophysin was excised from a 50-year-old woman. Treatments that followed were radiation therapy, and surgery plus radiation therapy and temozolom...

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Bibliographic Details
Published in:Clinical nuclear medicine 2015-07, Vol.40 (7), p.e363-e365
Main Authors: Savelli, Giordano, Muni, Alfredo
Format: Article
Language:English
Subjects:
Brain Neoplasms - diagnostic imaging
Brain Neoplasms - genetics
Female
Gene Deletion
Humans
Middle Aged
Multimodal Imaging
Oligodendroglioma - diagnostic imaging
Oligodendroglioma - genetics
Organometallic Compounds
Positron-Emission Tomography
Radiopharmaceuticals
Tomography, X-Ray Computed
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Summary:ABSTRACTSix years ago, a right frontal lobe anaplastic oligodendroglioma negative for AE1/AE3 and HBM-45, positive for 1p/19q deletion, EMA, GFAP, and synaptophysin was excised from a 50-year-old woman. Treatments that followed were radiation therapy, and surgery plus radiation therapy and temozolomide for a relapse with an early partial response, followed by disease progression. In the middle of last year, Ga-DOTANOC PET/CT was carried out to evaluate the possibility of treatment with peptide receptor radionuclide therapy. The examination revealed a grossly round-shaped uptake corresponding to the surgical wall, with some smaller uptakes disseminated in different parts of the brain.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0000000000000816