Treatment of advanced medullary thyroid cancer with an alternating combination of 5 FU-streptozocin and 5 FU-dacarbazine

Combinations of 5-fluorouracil (5-FU) and streptozocin and 5-FU and dacarbazine were given alternately to 20 patients with metastatic medullary thyroid carcinoma. Three partial responses and 11 long-term stabilizations were observed. No unexpected toxicity occurred.

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Bibliographic Details
Published in:British journal of cancer 1995-02, Vol.71 (2), p.363-365
Main Authors: SCHLUMBERGER, M, ABDELMOUMENE, N, DELISLE, M. J, COUETTE, J. E
Format: Article
Language:English
Subjects:
Antineoplastic agents
Biological and medical sciences
Chemotherapy
Medical sciences
Pharmacology. Drug treatments
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Description
Summary:Combinations of 5-fluorouracil (5-FU) and streptozocin and 5-FU and dacarbazine were given alternately to 20 patients with metastatic medullary thyroid carcinoma. Three partial responses and 11 long-term stabilizations were observed. No unexpected toxicity occurred.
ISSN:0007-0920
1532-1827
DOI:10.1038/bjc.1995.73