Genetic characterization of porcine circovirus type 2 in the Korean wild boar population

The porcine circovirus type 2 (PCV2) has reached very high levels in the pig population in South Korea and throughout the world since it was first described in the late 1990s. In this study, we found that the prevalence of PCV2 in the Korean wild boar population was 4.98% (91/1825). Interestingly, 1...

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Bibliographic Details
Published in:Veterinary microbiology 2014-03, Vol.169 (3-4), p.147-153
Main Authors: An, Dong-Jun, Lim, Seong-In, Kim, Yong Kwan, Lee, Hyun-Kyoung, Cho, Yoon-Young, Song, Jae-Young, Hyun, Bang-Hoon, Park, Bong-Kyun
Format: Article
Language:English
Subjects:
Animals
Antigens, Viral - genetics
Capsid Proteins - genetics
Circovirus - genetics
Genotype
Molecular Sequence Data
PCV2
Phylogeny
PMAL
Porcine circovirus
Republic of Korea
Selection, Genetic
Sus scrofa - virology
Swine
Swine Diseases - epidemiology
Swine Diseases - virology
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Summary:The porcine circovirus type 2 (PCV2) has reached very high levels in the pig population in South Korea and throughout the world since it was first described in the late 1990s. In this study, we found that the prevalence of PCV2 in the Korean wild boar population was 4.98% (91/1825). Interestingly, 19 PCV2 ORF2 sequences that could be completely sequenced showed that they belonged only to genotype PCV2b, subgroup 1A/B (n=16) and 1C (n=3). We suggest that sites potentially under positive selection are responsible for the antigenicity changes and phenotypic switch patterns in the capsid gene of 55 PCV2s from Korean domestic pigs, but the sites potentially under positive selection in the 19 PCV2 ORF2 genes from Korean wild boar are not responsible for antigenicity.
ISSN:0378-1135
1873-2542
DOI:10.1016/j.vetmic.2013.12.023