Sleep and sleep disorders in the elderly: Part 3: Restless legs syndrome

Restless legs syndrome (RLS) is a commonly occurring condition with a prevalence of approximately 10%. Women are more often affected than men. There is a primary and a secondary form. Secondary RLS is triggered by iron deficiency, severe renal insufficiency and many drugs and medications. The treatm...

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Bibliographic Details
Published in:Zeitschrift für Gerontologie und Geriatrie 2015-06, Vol.48 (4), p.379-87; quiz 388
Main Authors: Frohnhofen, H, Schlitzer, J
Format: Article
Language:ger
Subjects:
Aged
Anemia, Iron-Deficiency - complications
Cross-Sectional Studies
Dopamine Agonists - adverse effects
Dopamine Agonists - therapeutic use
Drug Combinations
Female
Germany
Humans
Levodopa - adverse effects
Levodopa - therapeutic use
Male
Naloxone - adverse effects
Naloxone - therapeutic use
Oxycodone - adverse effects
Oxycodone - therapeutic use
Restless Legs Syndrome - drug therapy
Restless Legs Syndrome - epidemiology
Restless Legs Syndrome - etiology
Risk Factors
Sex Factors
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Summary:Restless legs syndrome (RLS) is a commonly occurring condition with a prevalence of approximately 10%. Women are more often affected than men. There is a primary and a secondary form. Secondary RLS is triggered by iron deficiency, severe renal insufficiency and many drugs and medications. The treatment for RLS is always symptomatic. In addition to treating associated diseases, dopaminergic therapy is paramount. Pharmacotherapy encompasses levodopa (L-dopa) and dopamine agonists, such as pramipexole, ropinirole and rotigotine. A serious complication of dopaminergic therapy is the so-called augmentation. In the case of insufficient efficacy, severe discomfort or augmentation, oxycodone/naloxone is now approved for the treatment of RLS.
ISSN:1435-1269
DOI:10.1007/s00391-015-0901-4